Normal and Aging Hair Biology and Structure: Aging and Hair

January 2015 in “ Current problems in dermatology ”

Molly Goodier, Maria Hordinsky

minoxidil finasteride Coenzyme Q10 telomere shortening telogen phase anagen phase Rogaine Propecia CoQ10

TLDR Hair gets thinner, grayer, and changes texture with age due to genetics, environment, and cellular changes, affecting the growth cycle.

The document from 2015 examines the changes in hair biology and structure due to aging, noting that hair becomes thinner, grayer, and undergoes textural changes. It attributes these changes to factors like genetic influences, environmental damage, and molecular alterations such as telomere shortening and reduced cell numbers. The hair growth cycle is also affected, with an increased telogen phase and decreased anagen phase. Treatments such as minoxidil and finasteride are mentioned for combating hair aging, alongside potential benefits of Coenzyme Q10. The paper highlights the need for understanding these changes to create effective anti-aging hair treatments.

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