research Applications and Limitations of Lipid Nanoparticles in Dermal and Transdermal Drug Delivery via the Follicular Route
Lipid nanoparticles can help deliver drugs through hair follicles but struggle to penetrate deeper skin layers.
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660-690 / 713 resultsresearch Methotrexate for Maintenance of Remission in Ulcerative Colitis
Methotrexate is not proven to maintain remission in ulcerative colitis.
research Autotaxin–Lysophosphatidic Acid–LPA3 Signaling at the Embryo-Epithelial Boundary Controls Decidualization Pathways
LPA3 signaling in the uterus is crucial for placental formation and fetal development.
research Cidea Control of Lipid Storage and Secretion in Mouse and Human Sebaceous Glands
Cidea is essential for proper lipid storage and secretion in sebaceous glands, affecting skin and hair health.
research A Composite Model for the Transport of Hydrophilic and Lipophilic Compounds Across the Skin: Steady-State Behavior
The model better predicts how water-loving and fat-loving substances move through the skin by including tiny pores and hair follicle paths.
research Platelet-Derived Bio-Products: Classification Update, Applications, Concerns, and New Perspectives
Platelet-derived bio-products help in wound healing and tissue regeneration but lack standardized methods, and their use in medicine is growing.
research Biochemical and Structural Characteristics, Gene Regulation, Physiological, Pathological and Clinical Features of Lipocalin-Type Prostaglandin D2 Synthase as a Multifunctional Lipocalin
Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.
research A Comprehensive Review of Acne Vulgaris
Acne can't be cured but can be managed with treatments like benzoyl peroxide and diet changes; it's costly and can lead to scarring and mental health issues.
research Using WGCNA to Identify Hub Genes of Skin Hair Follicle Development in Fetal Stage of Inner Mongolia Cashmere Goat
Researchers found WNT10A to be a key gene in developing goat hair follicles.
research Toll-Like Receptor 4 (TLR4): New Insights into Immunity and Aging
TLR4 is important in aging-related diseases and could be a new treatment target.
research Ethosome: A Novel Vesicular Carrier for Transdermal Drug Delivery
Ethosomes are effective, safe carriers for delivering drugs through the skin.
research Cell Death in Skin Function, Inflammation, and Disease
Different types of cell death affect skin health and inflammation, and understanding them could improve treatments for skin diseases.
research Oil Body Bound Oleosin-rhFGF9 Fusion Protein Expressed in Safflower Stimulates Hair Growth and Wound Healing in Mice
A protein found in safflower seeds can stimulate hair growth and speed up wound healing in mice.
research The Importance of Natural Products in Cosmetics
Natural products like coconut oil and aloe vera are beneficial in cosmetics for their healing properties.
research Ultrastructure of the Contrasting Types of Keratinization Seen in the Tail Epidermis of the Laboratory Mouse Mus Musculus
Mouse tail skin has different keratinization near hair follicles and scales.
research Novel Anti-Aging Gene NM_026333 Contributes to Proton-Induced Aging via NCX1 Pathway
The gene NM_026333 slows down aging by affecting the NCX1 pathway and could be targeted for anti-aging treatments.
research Current Understanding of Androgenetic Alopecia: Part II: Clinical Aspects and Treatment
research PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds
Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
research Long-Term Administration of Triterpenoids From Ganoderma Lucidum Mitigates Age-Associated Brain Physiological Decline via Regulating Sphingolipid Metabolism and Enhancing Autophagy in Mice
Taking triterpenoids from Ganoderma lucidum over a long time can help slow down brain aging and improve overall health in mice.
research Autophagy: Guardian of Skin Barrier
Autophagy helps keep skin healthy and may improve treatments for skin diseases.
research Biallelic Variants in Lanosterol Synthase (LSS) Cause Palmoplantar Keratoderma-Congenital Alopecia Syndrome Type 2
Certain genetic changes in the LSS gene cause a rare skin and hair condition.
research Omega-6 Highly Unsaturated Fatty Acids in Leydig Cells Facilitate Male Sex Hormone Production
Omega-6 fats in certain cells boost male hormone production.
research Safflower Oil Body Nanoparticles Deliver hFGF10 to Hair Follicles and Reduce Microinflammation to Accelerate Hair Regeneration in Androgenetic Alopecia
Safflower oil nanoparticles can deliver hFGF10 to hair follicles, reduce inflammation, and potentially speed up hair growth in conditions causing hair loss.
research A Thing of Beauty Is a Joy Forever: Plants and Plant-Based Preparations for Facial Care in Suriname
Suriname uses many plants for beauty, with potential for a beauty industry, but more evidence is needed for product effectiveness.
research Transcriptome Analysis of Skin from SMP30/GNL Knockout Mice Reveals the Effect of Ascorbic Acid Deficiency on Skin and Hair
Vitamin C deficiency changes gene expression, affecting skin and hair health.
research Key Factors in the Complex and Coordinated Network of Skin Keratinization: Their Significance and Involvement in Common Skin Conditions
Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.
research Vitamin A Regulates Dermal Papilla Cell Proliferation and Apoptosis Under Heat Stress via IGF1 and Wnt10b Signaling
Vitamin A helps rabbit skin cells grow and survive heat stress.
research Clinical Efficacy of Topical or Oral Soy Supplementation in Dermatology: A Systematic Review
Soy supplements improve various skin conditions and aging signs, with topical use boosting skin barrier function.
research Cannabinoids and Their Receptors in Skin Diseases
Cannabinoids might help treat skin problems but more research is needed to be sure.
research Home Remedies in Dermatology
Many people use home remedies for skin conditions, but there's limited scientific evidence to support their effectiveness.