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The new chemotherapy combination for advanced lung cancer showed a 35.7% response rate but caused significant side effects.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

A combination of nanomilled oral testosterone and dutasteride normalized testosterone levels in men with low testosterone and is safe for short-term use.

Some existing medicines show promise as safe treatments to protect against the side effects of radiation therapy.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

The PS-b-PAA copolymer nanomicelles are effective for delivering a cancer treatment drug in photodynamic therapy.

Methotrexate is not proven to maintain remission in ulcerative colitis.

Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.

Caraway, Chinese chives, and cassia may improve health and prevent diseases due to their nutrients and medicinal properties.

Cynoglossum amabile has medicinal potential but poses safety concerns due to liver toxicity.

Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

The conclusion is that there is a high demand for new contraceptives that provide both pregnancy prevention and protection against STIs, along with additional health benefits.

The gel with special fat-loaded particles from rice bran could be an effective skin treatment for hair loss.

Scalp hypothermia can prevent chemotherapy-induced hair loss but is not suitable for all patients, and more research is needed to improve prevention methods.

Hair analysis can detect cocaine use but doesn't accurately show the amount or timing of use.

JAK inhibitors can effectively reverse hair loss in people with alopecia areata.

Five preservatives may disrupt hormone function and need more health and environmental risk assessment.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

MK-386 and finasteride together effectively reduce DHT levels, potentially treating acne and male pattern baldness.

Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.

PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.

Special gels help heal diabetic foot sores and reduce the risk of amputation or death.

Most drugs fail to reach the market, but understanding their properties and using strategies like early toxicity tests and drug repurposing can help advance their development.

Applying 5% minoxidil to fingernails can significantly increase their growth rate.

Biodegradable polymers can improve cannabinoid delivery but need more clinical trials.

Sorafenib causes skin reactions by increasing the number and activity of skin mast cells.

Nutraceuticals that promote hair growth do not reduce tamoxifen's effectiveness in breast cancer treatment.