June 2023 in “Skin Research and Technology” This study concluded that, in male patients with mild-to-moderate androgenetic alopecia, injections of PRP prepared by an automated method combined with topical 5% minoxidil were effective and safe, showing superior clinical efficacy and patient satisfaction compared to PRP alone.
January 2026 in “OSF Preprints (OSF Preprints)” In this study, researchers presented a novel therapeutic approach for androgenetic alopecia combining AR-PROTAC degradation with regenerative strategies and evaluated the potential of GT20029 as a topical treatment, proposing a three-phase protocol and future research hypotheses.
September 2023 in “Journal of Education, Health and Sport” This review examines the potential uses of platelet-rich plasma in dermatology, noting its growing therapeutic applications, but highlights the need for more standardized procedures and larger studies to confirm its effects.
2 citations
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February 2014 in “Animal Biotechnology” This study reported that the PTGER2 gene is strongly expressed in cashmere goat skin and its expression tends to decrease from the anagen to telogen stages of the hair follicle cycle.
This study explored the structure and function of lipocalin prostaglandin D synthase, revealing its dual role in substrate catalysis and as a lipophilic ligand carrier, potentially informing future drug delivery design.
47 citations
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December 2011 in “Experimental Dermatology” This study suggests that the neuropeptide CGRP may protect against, but not restore, IFNγ-induced collapse of hair follicle immune privilege in alopecia areata.
March 2026 in “Journal of Ovarian Research” This review explores the potential of platelet-rich plasma therapy for early ovarian reserve decline and premature ovarian insufficiency, indicating some ovarian function improvements in initial studies but highlighting the need for further research.
April 2026 in “Mathematics” This study used a probabilistic framework to show that platelet-rich plasma preparation results in significant variability in platelet dose due to factors like injected volume and concentration factor.
April 2025 in “Dermatologic Surgery” This article reports no new research findings and corrects the affiliation for Dr. Shao-Wen Li in a previous publication.
November 2025 in “Open Repository of the University of Porto (University of Porto)” This report covers an internship at a pharmacy and hospital where multiple pharmaceutical activities were examined, including the preparation of individualized medication and the comparison of drugs for hypercholesterolemia treatment.
14 citations
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January 2016 in “Biochemical and Biophysical Research Communications” In this study, researchers found that ginsenoside Re from Panax ginseng increased hair shaft length and duration in mice, comparable to minoxidil, by modulating TGF-β signaling pathways.
January 2025 in “JCEM Case Reports” This report describes two cases of glucocorticoid resistance syndrome highlighting genetic diversity; one patient improved with low-dose dexamethasone despite negative genetic testing, while the other is monitored with a novel NR3C1 variant.
2 citations
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June 2021 in “Cosmoderma” This article reviews the use of platelet-rich plasma (PRP) in various dermatological conditions and reports no new clinical results; the authors emphasize its efficacy and call for continued careful use.
October 2023 in “Peer review” This review discusses the efficacy and safety of using intradermotherapy combined with platelet-rich plasma for treating alopecia and reports no new clinical results.
513 citations
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February 2022 in “Advanced Science” This study demonstrated that incorporating PDA@Ag nanoparticles into a cationic guar gum hydrogel significantly enhanced photothermal conversion efficiency, achieving superior antibacterial efficacy both in vitro and in vivo, advancing the potential of PDA as a photothermal antibacterial agent.
848 citations
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October 2020 in “International Journal of Molecular Sciences” This review discusses the potential of platelet-rich plasma applications in regenerative medicine and explores recent progress and challenges in translating non-clinical PRP findings into human treatments, but reports no new clinical results.
29 citations
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March 2016 in “Dermatologic therapy” In this study, a patient with lichen planopillaris experienced complete resolution of itching and hair shedding following treatment with a new platelet-rich plasma regimen, marking the first reported success in this context.
This study identified CXXC5 as a key mediator of hair loss induced by PGD2 and DHT via suppression of the Wnt/β-catenin pathway, with implications for potential therapeutic targets.
April 2017 in “Plastic surgical nursing” Platelet-rich plasma (PRP) is an effective treatment for hair loss that involves scalp injections and requires ongoing maintenance.
3 citations
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September 2018 in “Current Drug Delivery” This study found that a finasteride topical gel formulation using propylene glycol and Tween® 80 showed significantly enhanced permeation compared to a control formulation without these enhancers.
January 2024 in “Dermatologic Therapy” This study reported that in patients with androgenic alopecia, platelet-rich plasma therapy's effectiveness in enhancing hair density and caliber was positively correlated with specific growth factor concentrations, notably glial cell-derived neurotrophic factor and platelet-derived growth factor-BB, while no significant correlations were found with demographic factors.
April 2023 in “International journal of science and research” In this study, PRP treatment improved hair loss in 40 female patients with female pattern alopecia, with most progressing to better grades of hair coverage after 6 months, while only minor pain was occasionally reported as an adverse effect.
1 citations
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January 2021 This review discusses the historical development and dermatological applications of platelet-rich plasma, emphasizing its potential for treating androgenic alopecia and other skin conditions, but reports no new clinical results.
April 2023 in “Journal of Investigative Dermatology” This study found that patients receiving PRP treatments for various types of alopecia and skin rejuvenation had a higher risk of adverse events and lower self-assessment scores when injections were administered at shallower depths, with significant correlations between patient and physician assessments across different indications.
86 citations
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February 2009 in “Journal of Neuroscience” This study found that during late pregnancy in rats, there is an increase in extrasynaptic GABA A receptor number in granule cells of the dentate gyrus, linked to hormonal fluctuations.
June 2020 in “Journal of Evolution of medical and Dental Sciences” This study found that platelet-rich plasma treatment effectively decreased hair fall and increased hair growth in male patients with androgenetic alopecia.
1 citations
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April 2013 in “The FASEB Journal” In this study, chronic finasteride administration in near-term pregnant rats restored baroreflex control of renal sympathetic nerve activity to levels observed in non-pregnant rats.
12 citations
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October 2017 in “Journal of Cosmetic Dermatology” This study found that plasma rich in growth factors (PRGF) as an adjuvant to follicular unit extraction (FUE) surgery may enhance hair graft performance and reduce post-surgical inflammation and pain in hair loss patients.
January 2005 in “Belarusian State Pedagogical University repository (Belarusian State Pedagogical University)” In this study, a 0.5% addition of TPGS to topical minoxidil solutions increased hair growth in mice, but higher concentrations reduced this benefit.
102 citations
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July 2007 in “Genes & Development” This study found that maternal PPARγ is essential for preventing the production of inflammatory lipids in mouse milk, which can otherwise cause inflammation, alopecia, and growth retardation in nursing pups.