Clinical Technique and Outcomes of Platelet-Rich Plasma Application for Treatment of Androgenic and Scarring Alopecia, Acne Scarring, Melasma, and Facial Rejuvenation: A Prospective Multicenter Study

    April 2023 in “ Journal of Investigative Dermatology ”
    L. Dave, U. Nadir, M. Yi, F. Ikmal-Hisham, B. Kang, R. Pearlman, F. Walocko, M. Alam
    Image of study
    TLDR Platelet-rich plasma treatment is generally safe and effective for hair loss, acne scars, skin discoloration, and facial rejuvenation, but deeper injections are better and multiple treatments can increase risk of side effects.
    This multicenter study involved 532 participants, primarily female (67%) and Caucasian (83%), who were treated with platelet-rich plasma (PRP) for conditions such as androgenic alopecia, scarring alopecia, alopecia areata, acne scarring, melasma, and facial rejuvenation. The typical patient had androgenic alopecia and received around 40 injections of PRP per visit without adverse events. However, patients who received 2 or more treatments had a significantly increased risk of adverse events when the injection depth was subcutis and superficial dermis versus deep dermis. Patient self-assessment scores were also significantly lower when the injection depth was subcutis compared to deep dermis. Patient and physician global assessment scores were significantly positively correlated for most indications.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 108 results
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Losing Hair on Dutasteride? You might have LPP

      in Research/Science  97 upvotes 7 months ago
      Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.

      community Story time! The Great Unbalding (PP405)

      in Research/Science  223 upvotes 1 week ago
      PP405 is a promising new hair loss treatment that may reactivate dormant hair follicles without side effects. It could surpass traditional treatments like minoxidil and finasteride if successful in further trials.

      community Anyone who is not taking fin after hair transplant, how is you hair now?

      in Transplants  81 upvotes 2 years ago
      The conversation is about the effectiveness of finasteride (fin) in preventing hair loss after a hair transplant. Some users have experienced hair thinning and loss after stopping finasteride, while others have had success with finasteride and minoxidil (min) in maintaining their transplanted hair. The general consensus is that finasteride is important for younger patients to prevent further hair loss.

    Related Research

    6 / 6 results