December 2015 in “OPAL (Open@LaTrobe) (La Trobe University)” This source provides procedural details without reporting new experimental findings or conclusions.
138 citations
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November 2015 in “Journal of Pharmacology and Experimental Therapeutics” This review discusses the mechanisms associated with protoporphyrin IX in living cells and reports no clinical results; the authors emphasize its potential in cancer diagnosis and the risks of toxicity.
56 citations
,
March 1991 in “Journal of Investigative Dermatology”
January 2024 in “Journal of Education, Health and Sport” This review discusses the potential benefits of platelet-rich plasma (PRP) for treating androgenic alopecia in athletes and examines how physical activity might influence androgen levels, but it reports no new results.
October 2025 in “Frontiers in Toxicology” This study found that a human relevant potency threshold for estrogen receptor alpha agonism may serve as a health-protective screening tool, and highlights inference performance as essential for scientific confidence frameworks.
5 citations
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March 2022 in “Frontiers in Medicine” This review analyzed 17 recent clinical trials on platelet-rich plasma for androgenetic alopecia but reports no new clinical results; the authors seek a consensus on optimal PRP use.
12 citations
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August 2021 in “International Journal of Biological Macromolecules” This study observed that Poria cocos polysaccharides and finasteride both reduced inflammation in chronic nonbacterial prostatitis in rats, but only Poria cocos polysaccharides reversed related changes in the gut microbiota.
14 citations
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March 2023 in “Bioengineering” In this retrospective study at Lausanne University Hospital, 61% of 48 patients with tendinopathies reported favorable outcomes after a single standardized autologous PRP injection, while 36% needed two, and effectiveness was unrelated to platelet concentration, activity level, age, or gender.
June 2020 in “Journal of Investigative Dermatology” This study found that FDA-cleared devices for preparing platelet-rich plasma showed inconsistent product quality, with variable platelet counts and inadequate quality control performance, suggesting clinical improvement may not rely on platelet concentration.
March 2022 in “Benha Journal of Applied Sciences” This study found that serum PGRN levels and HOMA-IR were significantly higher in male AGA patients compared to controls, suggesting a link to insulin resistance and metabolic syndrome.
1 citations
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January 2024 in “Advances in Orthopedics” This review concludes that platelet-rich plasma injections significantly improve knee joint function in managing knee osteoarthritis compared to other treatments.
16 citations
,
August 2023 in “Tissue Engineering and Regenerative Medicine”
1 citations
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November 2020 in “Journal of The American Academy of Dermatology” This study highlights criticisms of existing research on PRP as a treatment for androgenetic alopecia, noting small sample sizes, lack of controls, subjective result analysis, and varied methodologies.
22 citations
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January 2001 in “Chemical & Pharmaceutical Bulletin” This study found that two new progesterone derivatives showed higher antiandrogenic effects and 5α-reductase inhibition than finasteride in hamsters, particularly reducing seminal vesicle weight and flank organ size.
39 citations
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January 2020 in “Frontiers in Genetics” This study found that stage-specific epigenetic changes, particularly involving the gene PDGFC, may affect wool fiber development in Zhongwei goats, potentially serving as a biomarker for fur goat selection.
November 2025 in “Advanced Therapeutics” This review examines platelet-rich plasma therapy's multidisciplinary applications in regenerative medicine and discusses preparation challenges but presents no new clinical results.
This study found that isolated human scalp hair follicles express PGE2 genes and EP2 protein, suggesting PGE2 may play a crucial role in regulating hair growth.
1 citations
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April 2011 in “The FASEB Journal” This study suggests that the regulation of GABA‐A δ subunit expression by ovarian progesterone-derived neurosteroids may influence seizure susceptibility in catamenial epilepsy.
November 2023 in “Scientific Papers Journal VETERINARY SERIES” This review highlights the potential of platelet-rich plasma as a therapeutic tool in animals, noting its mixed efficacy and promising applications in areas like reproduction, but reports no new clinical results.
October 2023 in “Aesthetic Plastic Surgery” Platelet-rich plasma treatment for hair loss may improve patients' quality of life.
November 2015 in “Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)” This study concluded that platelet concentrates can promote both soft and hard tissue regeneration, suggesting their potential application in clinical regenerative therapies.
November 2003 in “Journal of Neurochemistry” This study suggests that the neurosteroid allopregnanolone may play a crucial role in how ethanol affects neurons related to alcohol addiction vulnerability.
32 citations
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January 2000 in “International Journal of Cancer” In this study, the researchers observed significant down-regulation of Transglutaminase-3 expression in esophageal cancer tissues compared to normal tissues, suggesting its alteration is a common event in esophageal cancer development.
17 citations
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April 2006 in “Brain Research” This study found that stimulation with certain neurotransmitters and hormones suggests the involvement of 5α-reduced neurosteroids in glial cell differentiation in rat C6 glioma cells.
November 2025 in “International Journal of Molecular Sciences” This review covers the diverse clinical applications of platelet-rich plasma in regenerative medicine but provides no new clinical results.
January 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review discusses the evidence for platelet-rich plasma as a promising treatment for androgenetic alopecia, highlighting its potential benefits and favorable safety profile but noting the need for standardized protocols and larger trials.
136 citations
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April 2016 in “Dermatologic Surgery” This study found that platelet-rich plasma significantly increased hair density and anagen hair proportions in androgenetic alopecia patients, suggesting potential as an adjuvant therapy.
16 citations
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January 2017 in “Physical chemistry chemical physics/PCCP. Physical chemistry chemical physics” This study presents computational modeling and experimental analysis of the HGT protein KAP8.1, identifying key structural features that may influence hair's response to environmental conditions.
269 citations
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May 2002 in “Hormones and Behavior” Lowering 3α,5α-THP in the hippocampus increases anxiety and depression in proestrous rats.
180 citations
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June 2004 in “Journal of Pharmacology and Experimental Therapeutics” This study found that progesterone's antiseizure effects in mice occurred primarily through conversion to allopregnanolone, rather than through the progesterone receptor, as evidenced by results in PR knockout mice.