Platelet-Rich Plasma in Androgenetic Alopecia: An Evidence-Based Clinical and Biological Review

January 2026 in “ Zenodo (CERN European Organization for Nuclear Research) ”

Prabhu Chandra Mishra

platelet-rich plasma androgenetic alopecia hair density hair shaft thickness global photographic scores randomized controlled trials prospective studies systematic reviews PRP AGA

TLDR PRP therapy can improve hair growth in early to moderate hair loss but needs standardized methods for consistent results.

This review evaluates the efficacy, mechanisms, safety, and clinical application of platelet-rich plasma (PRP) in treating androgenetic alopecia (AGA). The analysis of randomized controlled trials, prospective studies, and systematic reviews from 2013 to 2025 indicates that PRP therapy significantly improves hair density, hair shaft thickness, and global photographic scores. Despite these positive outcomes, variations in preparation protocols and assessment methods hinder comparability across studies. PRP is generally safe with minimal adverse events, making it a promising treatment for early to moderate AGA. However, standardization of preparation techniques and large-scale, long-term randomized trials are necessary to establish definitive treatment guidelines.

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