85 citations
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January 1996 in “International Journal of Cancer”
In this study, AS101 combined with chemotherapy significantly reduced the severity of chemotherapy-induced alopecia in non-small-cell-lung-cancer patients and may involve immune mechanisms related to IL-1 and PGE2.
This study systematically reviewed meta-analyses and Mendelian randomization studies to identify factors influencing prostate cancer risk, finding suggestive associations for physical activity, height, and smoking but no robust, convincing overlapping evidence across tested factors.
January 2024 in “Journal of Pharmacognosy and Phytochemistry”
This paper reviewed the medicinal properties and historical Unani uses of Ranunculus sceleratus (Kabīkaj), detailing its identification, uses, and both beneficial and adverse effects, while noting its current lack of use due to availability and identification challenges.
37 citations
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August 2022 in “Frontiers in pharmacology”
This study found that oral JAK inhibitors are effective and generally well-tolerated for treating alopecia areata, but high recurrence rates after stopping treatment suggest the need for continuous use.
Finasteride can regrow hair but may cause depression and suicidal thoughts in some users. The connection between finasteride and mental health issues is debated, with some attributing it to pre-existing conditions or stress.
Baldness is not an evolutionary disadvantage because it occurs after reproductive age. Treatments like Minoxidil and Finasteride are used for androgenetic alopecia but don't address the root cause.
Many users report better results with finasteride than dutasteride for hair loss, despite studies suggesting otherwise. Some suggest that dutasteride's effectiveness may depend on the delivery method, such as using lipids for absorption.
Dutasteride reduces DHT more effectively than finasteride, but finasteride is more commonly used and approved for hair loss. Users have mixed opinions on dutasteride's effectiveness, with some experiencing better results and others facing side effects or no improvement.
Beta-sitosterol may inhibit 5-alpha reductase type 2 enzyme, potentially reducing DHT levels and promoting hair growth, similar to finasteride but possibly with fewer side effects. Its effectiveness and side effects compared to other treatments like saw palmetto and finasteride remain uncertain due to limited research.