Addressing Knee Osteoarthritis Pathology Through Platelet-Rich Plasma Treatment: A Comprehensive Review

This review concludes that platelet-rich plasma injections significantly improve knee joint function compared to alternative treatments in managing knee osteoarthritis.

The authors concluded that while PRP is a promising and well-tolerated treatment for early to moderate knee osteoarthritis, standardizing preparation protocols, patient selection, and outcome reporting is crucial to enhance comparability and inform clinical practice.

This review highlights that PRP shows promise as an effective and safe treatment for knee osteoarthritis, particularly in mild-to-moderate stages, but underscores the need for standardized protocols and further research.

This study found that a single dose of PRP with 100 billion platelets significantly reduced pain and improved knee function in patients with osteoarthritis, but did not alter joint structure on MRI.

This review describes and compares the efficacy of bioregenerative therapies, specifically mesenchymal stem cells and platelet-rich plasma, for treating osteoarthritis, suggesting they may offer a less invasive and more effective alternative to surgery and conventional therapies.