1 citations
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November 2024 in “Orphanet Journal of Rare Diseases” Changes in genes FGA, VWF, and ACTG1 may contribute to pemphigus vulgaris.
September 2020 in “Oxford University Press eBooks” This article discusses how understanding a genetic condition with a 5-alpha reductase mutation led to developing finasteride to treat benign prostatic hyperplasia and male pattern baldness, reporting no new research results.
April 2026 in “JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA” In this study, the researchers successfully developed a Spanlastic gel containing EGCG for transdermal application, significantly increasing EGCG skin permeability with optimal entrapment efficiency, zeta potential, and vesicle size.
August 2001 in “대한구강악안면외과학회지” This study found that subcutaneous administration of decorin at doses of 10 and 20 μg reduced scar formation by decreasing the thickness of immature collagen fibers in rabbit surgical wounds.
151 citations
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August 2011 in “The EMBO Journal” The enzyme PA-PLA1α is important for proper hair follicle development.
23 citations
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June 2012 in “Molecular Biology Reports” This study found that human outer root sheath cells express VEGF receptor-2, and exogenous VEGF165 significantly stimulates their proliferation through activation of the ERK signaling pathway.
70 citations
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June 2017 in “Nature Communications” This study introduced a new technique, 2Phatal, enabling precise apoptotic cell ablation in living animals, revealing unique cell-type differences in apoptosis-related dynamics.
14 citations
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November 2009 in “Clinical and experimental dermatology” This article presents a case report of a child with coexisting alopecia areata and vitiligo showing improvement with topical prostaglandin E2 treatment, without reporting new clinical results.
3 citations
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April 2021 in “PLoS ONE” The authors concluded that controlling voltage, pulse width, and calcium concentration in pulse electric field-activated platelet-rich plasma enhances the release of growth factors and serotonin without causing clot formation, suggesting potential clinical advantages over bovine thrombin-activated PRP.
1 citations
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July 2022 in “Indian Journal of Dermatology” This report describes the first documented case of bullous pyoderma gangrenosum developing on a cesarean section scar, which improved rapidly with oral prednisolone.
3 citations
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October 2023 in “Bioscience Biotechnology and Biochemistry” In this animal study, researchers found that daily oral intake of salmon nasal cartilage proteoglycan enhanced hair growth in mice, potentially through a signaling pathway that stimulates specific growth factors in human follicle cells.
3 citations
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May 2021 in “Archiv der Pharmazie” This study found that the FGF-2 mimetic SUN11602 and VEGF mimetic ONO-1301 had unique effects on skin fibroblasts and keratinocytes, indicating potential for improving wound healing.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This paper provides an auditable companion package for their exploratory re-analysis of miRNA dysregulation and target enrichment in female pattern hair loss cases, focusing on candidate-level results from a public dataset comparison between affected individuals and healthy controls.
April 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this study, researchers conducted an exploratory re-analysis of miRNA dysregulation and aging-related target enrichment in female pattern hair loss using data from public GEO dataset GSE106780. The findings are preliminary and should be interpreted as candidate-level results due to the small sample size.
44 citations
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April 2013 in “Proceedings of the National Academy of Sciences of the United States of America” This study found a significant association between reduced FGF13 levels and X-linked congenital generalized hypertrichosis, suggesting FGF13's potential role in hair follicle growth and the hair cycle.
April 2026 in “Inflammopharmacology” This study found that Punica granatum ethanolic leaf extract may alleviate skin fibrosis in rats by modulating inflammation-related pathways and reducing dermal alterations.
28 citations
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August 2014 in “Journal of Assisted Reproduction and Genetics” This study found that the VEGF +405G/C polymorphism may be an inheritable risk factor for polycystic ovary syndrome in south Indian women.
546 citations
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February 2008 in “PLANT PHYSIOLOGY” This study found that overexpression of OsPHR2 in rice leads to increased phosphate accumulation and root architecture changes even under phosphate-sufficient conditions.
June 2026 in “Materials Today Communications” This study reported that a newly designed multifunctional conductive hydrogel, PrM, combined with electrical stimulation significantly accelerated wound healing, achieving 95.9% healing in a mouse model on day 10, by enhancing regenerative processes and downregulating TNF-α signaling under electrical treatment.
5 citations
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October 2015 in “The American journal of pathology” This study found that a spontaneous deletion in the Dsg3 gene of mice leads to hypomorphic desmoglein 3 expression, resulting in severe immunodeficiency, cyclic hair loss, and wasting disease, without causing the blistering typical of pemphigus vulgaris.
99 citations
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January 2004 in “Journal of Biological Chemistry” This study found that methylprednisolone can block IgG-induced keratinocyte detachment in an animal model of pemphigus vulgaris, potentially by increasing the synthesis and modifying adhesion molecules.
April 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The researchers reported that disrupting the RPGRIP1L gene in mice impaired desmosome function, causing skin blistering, and their findings suggest that PKCβII inhibition could help treat pemphigus.
1 citations
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January 2014 in “Turkish Journal of Ophthalmology” This case report highlights a rare side effect of prostaglandin analogues, detailing prostaglandin-associated periorbitopathy in three glaucoma patients treated with bimatoprost and travoprost.
32 citations
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December 2015 in “PloS one” This study found that applying a topical inhibitor of TGF-β1 may enhance scar maturation and improve the appearance of hypertrophic scars in a nude mouse model after two weeks.
This study found that FGF5 alternative spliceosomes inhibit dermal papilla cell proliferation and regulate hair follicle growth-related gene expression, impacting hair follicle development in rabbits.
October 2021 in “QJM: An International Journal of Medicine” In this pilot study, treatment with lyophilized platelet derived growth factors showed improvement in women with androgenetic alopecia, suggesting it may be a promising new therapy.
In this study, fibroblast growth factors promoted dermal papilla cell proliferation and showed potential for treating androgenic alopecia, with possible advantages over minoxidil in cellular organization and health.
June 2005 in “Key Engineering Materials” This study found that biodegradable hydrogels loaded with various growth factors significantly enhanced hair follicle growth and blood vessel formation in mice, demonstrating a positive effect on their hair growth cycle.
10 citations
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July 2023 in “Pharmaceutics” In this study using mice and human keratinocyte cells, researchers found that activating PKM2-mediated glycolysis and Wnt/β-catenin signaling, particularly via combined treatments, significantly accelerated wound healing and induced angiogenesis in wound beds.
2 citations
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April 2024 in “Cosmetics” This study investigated non-laser methods for removing permanent makeup using plant extracts, testing their decolorization effects on mice through tattooing and electroporation techniques.