Regulation of Hair Follicle Growth and Development by Different Alternative Spliceosomes of FGF5 in Rabbits

    March 2024 in “ Genes ”
    Shuang Sun, Bohao Zhao, Jiali Li … Xinsheng Wu
    Studysummary This study found that FGF5 alternative spliceosomes inhibit dermal papilla cell proliferation and regulate hair follicle growth-related gene expression, impacting hair follicle development in rabbits.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 11

    1. A Homozygous Missense Mutation in the Fibroblast Growth Factor 5 Gene Is Associated with the Long-Hair Trait in Angora Rabbits BMC genomics · 2023
    2. DNA Methylation Mediates LncRNA2919 Regulation of Hair Follicle Regeneration International Journal of Molecular Sciences · 2022
    3. Suppression of FGF5 and FGF18 Expression by Cholesterol-Modified siRNAs Promotes Hair Growth in Mice Frontiers in Pharmacology · 2021
    4. Bioinformatics Analysis of Evolutionary Characteristics and Biochemical Structure of FGF5 Gene in Sheep Gene · 2019
    5. Fibroblast Growth Factor 5-Short (FGF5s) Inhibits the Activity of FGF5 in Primary and Secondary Hair Follicle Dermal Papilla Cells of Cashmere Goats Gene · 2015
    6. FGF5 Is a Crucial Regulator of Hair Length in Humans Proceedings of the National Academy of Sciences of the United States of America · 2014
    7. Four Independent Mutations in the Feline Fibroblast Growth Factor 5 Gene Determine the Long-Haired Phenotype in Domestic Cats Journal of Heredity · 2007
    8. The Long And The Short Of It: Evidence That FGF5 Is A Major Determinant Of Canine Hair-Itability Animal genetics · 2006
    9. Molecular Mechanisms Regulating Hair Follicle Development ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2002
    10. Hair Follicle Apoptosis And Bcl-2 Journal of Investigative Dermatology Symposium Proceedings · 1999
    11. Transforming Growth Factor-β Receptor Type I and Type II Expression During Murine Hair Follicle Development and Cycling Journal of Investigative Dermatology · 1997

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    1. Progenic Hair Regrowth Treatment: The Use of Platelet-Released Growth Factors for Treating Androgenetic Alopecia by Activating Hair Follicle Stem Cells Journal of clinical & experimental dermatology research · 2014
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