June 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Prostaglandin D2, found in higher levels in bald scalps, stops hair growth and could be a target for treating hair loss.
May 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Prostaglandin D2, found in higher levels in bald scalps, stops hair growth, suggesting that blocking its receptor could potentially treat hair loss.
2 citations
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August 2024 in “Indian Dermatology Online Journal” Premature graying of hair is mainly caused by genetics, stress, and environment, with potential treatments being explored.
1 citations
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October 2022 in “Biomedicines” This study found that Prdm1 is crucial for whisker development in mice, affecting multiple signaling pathways and possibly playing a role in primates' evolutionary loss of vibrissae.
1 citations
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January 2022 in “Faculty reviews” This review discusses recent advances in understanding hair growth mechanisms and reviews current and emerging therapies, but it presents no new clinical results.
1 citations
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December 2019 in “Clinical ophthalmology” This study found that bimatoprost eye drops increased eyelash length, thickness, pigmentation, and the number of eyelashes per follicle in rabbits, without causing inflammation.
1 citations
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December 2019 This study found that bimatoprost eye drops significantly increased eyelash length, thickness, pigmentation, and the number of eyelashes per follicle in rabbits within one month.
April 2025 in “International Journal of Molecular Sciences” This review highlights the limitations of existing hair loss treatments like minoxidil and finasteride and suggests that future therapies may benefit from focusing on antibody and cell-based treatments, which offer targeted and potentially transformative options for managing hair loss disorders.
January 2025 in “Cellular & Molecular Biology Letters” This review discusses how dysregulated levels of eicosanoids, which are metabolites of phospholipids, may contribute to skin diseases like psoriasis and atopic dermatitis, suggesting the importance of targeted eicosanoid control in diagnosis and treatment.
21 citations
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March 2023 in “Journal of Crohn s and Colitis” This study suggests that microvascular damage and platelet deregulation may persist in ulcerative colitis patients even during remission, remaining as disease-associated molecular signatures.
20 citations
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January 2003 in “Dermatology online journal” This review discusses the potential of prostaglandin analogs for hair growth and forms of alopecia, and reports no new clinical results.
18 citations
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January 2019 in “European journal of histochemistry” This study found that in bovine skin, leptin and its receptor are expressed in the epidermis and hair follicles, suggesting a role in epidermis growth and hair follicle cycling through paracrine and autocrine mechanisms.
12 citations
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April 2019 in “Scientific Reports” This study found that HMGB1 enhanced hair growth by stimulating PGE2 production in human dermal papilla cells, suggesting a potential therapeutic target for alopecia treatment.
8 citations
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November 2019 in “Clinical Science” This study found that higher levels of DHA from omega-3 fatty acids delayed inflammation resolution and impaired wound healing quality in both transgenic mice and wild-type mice supplemented with DHA.
4 citations
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January 2023 in “Marine Drugs” This review explores enzyme inhibitors from gorgonians and soft corals and highlights their potential industrial and biomedical applications, but it reports no new experimental results.
3 citations
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September 2025 in “Neural Regeneration Research” This review discusses the roles of prostaglandins in the nervous system and their therapeutic potential for neurological diseases, noting their complex interactions with immune cells and signaling pathways.
1 citations
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March 2023 in “Frontiers in Medicine” This meta-analysis found that topical prostaglandin analogs could significantly improve hair length and density in patients with hair loss, compared to placebo, without notable safety differences.
1 citations
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February 2017 in “MOJ bioequivalence & bioavailability” This review discusses recent advancements in understanding the pathophysiology of androgenetic alopecia and highlights the potential for multilateral topical therapies to improve treatment efficacy with fewer side effects; it reports no new clinical results.
November 2025 in “International Journal of Molecular Sciences” This review highlights various treatments for androgenetic alopecia that target its underlying pathophysiological mechanisms, reporting enhanced hair growth, especially when combining drugs, which shows improved outcomes over individual drug use alone.
January 2025 in “Dermatologic Therapy” In this review, researchers explored key mechanisms underlying androgenetic alopecia, revealing how hormonal, oxidative, inflammatory, and lipid dysregulation suppress hair growth pathways and suggesting new therapeutic targets such as DP2 antagonists and microbiome modulators.
August 2024 in “Cosmetics” This review discusses genetic and pharmacogenetic insights, along with RNA interference technologies, for developing personalized therapies for androgenetic alopecia, yet presents no new clinical results.
June 2024 in “American Journal of Biomedical Science & Research” This article discusses male androgenetic alopecia, describing its progression and pattern, and reports no new findings or clinical results.
March 2024 in “Dermatology and therapy (Internet)” This study identified eight genetic markers associated with androgenetic alopecia, suggesting that these SNPs could influence individualized therapeutic responses and highlight the need for personalized treatment strategies.
January 2024 in “JOJ Dermatology & Cosmetics” This article discusses a trial evaluating patient satisfaction with the TH07 treatment for androgenetic alopecia but reports no clinical results.
February 2016 in “Faculty of 1000 Research Ltd” This review describes human hair follicle behavior and suggests that glycans may play a key role in controlling hair follicle growth, but reports no new clinical results.
February 2016 in “Faculty of 1000 Research Ltd” This review describes the dual influences on hair follicle homeostasis, proposing it as a "Yin Yang" paradigm, and highlights glycans as a potential key in hair follicle growth control; no new clinical results are reported.
June 2013 in “International Journal of Dermatology” This study found that among HIV-infected women, central lipohypertrophy was associated with shorter eyelashes but not changes in scalp hair texture or inflammation.
December 2022 in “Molecular Pharmaceutics” This study found that encapsulating latanoprost in nanotransfersomes increased skin penetration and improved its cell proliferation effect in vitro, suggesting potential for treating hair growth disorders.
September 2019 in “Journal of Investigative Dermatology” This study found that finasteride treatment reduced urinary androgen and prostaglandin levels in male pattern baldness patients to levels similar to healthy controls.
October 2019 in “FOOD SCIENCE RESEARCH JOURNAL” This study found that a high percentage of adolescent girls in Kanpur reported various clinical health problems and lacked nutritional awareness.