2 citations
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January 2023 in “Eastern Journal Of Medicine” This review discusses the use, efficiency, and preparation methods of autologous platelet concentrates in wound healing and periodontal regeneration, but it reports no new clinical findings.
April 2024 in “Research Square (Research Square)” This study found that extracts of mesenchymal stem cells (MSC-extract) and their protein components (MSC-protein) enhanced the proliferation and migration of periodontal ligament cells and induced significant periodontal tissue regeneration, showing potential as a new cell-free treatment for periodontal disease.
3 citations
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December 2016 in “Springer eBooks” This study found that activating Toll-like receptor 3 in periodontal ligament stem cells enhanced their stem cell and immunosuppressive properties, potentially supporting effective periodontal tissue regeneration.
April 2023 in “Dentistry” This chapter reviews the potential of stem cells from discarded deciduous teeth in regenerative medicine and dentistry, with no new clinical results presented.
11 citations
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August 2019 in “Journal of Molecular Histology” This study found that upregulation of NFIC may enhance proliferation and osteogenic/cementogenic differentiation in rat dental follicle cells.
10 citations
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May 2020 in “Clinical and Experimental Health Sciences” This study found that Tideglusib at 50nM stimulated Type-I collagen production in human gingival fibroblasts and osteoblasts, suggesting potential benefits for bone regeneration.
May 2022 in “Acta scientific dental sciences” This article discusses the use of platelet concentrates in regenerative surgeries for periodontal and bone defects but presents no new clinical results, emphasizing their potential benefits over traditional methods.
1 citations
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August 2023 in “Journal of Dentomaxillofacial Science” This study found that freeze-dried homologous platelet-rich plasma (FD HPRP) increased osteocalcin levels in cultured osteoblasts, suggesting its potential to support bone regeneration in periodontal treatment.
36 citations
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October 2023 in “Periodontology 2000” This narrative review concluded that autologous platelet concentrates, particularly L-PRF, effectively enhance bone and soft tissue healing in periodontal regenerative procedures, with L-PRF demonstrating the most convincing results and ease of use.
January 2006 in “Elsevier eBooks” This review discusses the regeneration capabilities of various vertebrate tissues, focusing on the unique ability of certain species to regenerate teeth and lens, and reports no new results.
1 citations
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December 2024 in “Pomeranian Journal of Life Sciences” This review found that microneedling can stimulate various biological pathways to promote tissue remodeling, enhance skin regeneration, and benefit conditions like wound healing and skin rejuvenation, with emerging uses in targeted drug delivery and periodontal therapy.
In this book, the authors provide an accessible overview of platelet concentrates and their dental applications, highlighting their role in tissue healing and regeneration, and reviewing recent studies on their efficacy in periodontal therapy, implant dentistry, and oral surgery.
December 2021 in “Figshare” This study found that BBS7 is important for Sonic hedgehog signaling activity, which may be crucial for maintaining periodontal ligament homeostasis in occlusal hypofunction.
November 2023 in “Periodontology 2000” This narrative review examines the technological advancements and clinical applications of liquid injectable platelet-rich fibrin (i-PRF), discussing its use across regenerative periodontology, sports medicine, and more, as well as its potential as a drug delivery system.
January 2012 in “Elsevier eBooks” This chapter reviews therapies for skin and corneal regeneration and hair loss, discussing various treatments but presenting no new research findings.
January 2019 in “Springer eBooks” Micrografts are useful for healing wounds, regenerating bone and periodontal tissues, and improving hair transplantation outcomes.
October 2025 in “The Scientific Issues of Ternopil Volodymyr Hnatiuk National Pedagogical University Series pedagogy” This study reviews modern techniques for bone tissue regeneration, addressing challenges like inadequate bone volume for dental implants, and highlights emerging methods such as guided bone regeneration, distraction osteogenesis, and stem cell therapy; it emphasizes the importance of personalized strategies tailored to individual patient needs.
1 citations
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September 2017 in “RGO - Revista Gaúcha de Odontologia” This review discusses the current understanding of tooth-derived stem cells for periodontal tissue engineering and highlights the heterogeneity and lack of standardization in selecting appropriate stem cell populations; it reports no new experimental results.
87 citations
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March 2020 in “Australian Dental Journal” This review discusses different preparation and application methods of platelet-rich plasma in dental regenerative medicine and reports no new results, highlighting its potential and associated controversies.
101 citations
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December 2014 in “Stem Cells and Cloning Advances and Applications” This article reviews the potential and current applications of adult oral stem cells in regenerative medicine, highlighting promising animal model results but noting that few human clinical trials have yet been conducted.
138 citations
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June 2019 in “Stem Cells and Development” This review explores the potential of periodontal ligament stem cells for regenerative therapy in periodontium, despite challenges due to their rarity, and reports no clinical results.
4 citations
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January 2013 in “Inflammation and Regeneration” This review examines recent developments in tooth regeneration therapies using mesenchymal stem cells, but it reports no new clinical findings.
66 citations
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May 2012 in “Scientific Reports” This study demonstrated that bioengineered hair follicles reconstituted from embryonic skin cells and transplanted into hosts can restore physiological hair functions, suggesting potential applications for treating alopecia.
12 citations
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September 2021 in “The International Journal of Developmental Biology” This review updates on the development of liposomal carriers for delivering growth factors to improve tissue regeneration and highlights recent efforts to enhance their stability and retention in tissues.
220 citations
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March 2020 in “Advanced functional materials” This review discusses the mechanisms and potential therapeutic benefits of mesenchymal stromal cell-derived extracellular vesicles delivered via biomaterials, but reports no new clinical results.
78 citations
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October 2012 in “Biomaterials” This study found that both human and rat dermal papilla spheroids can induce hair follicle neogenesis, but larger spheroids increase inductivity without significantly affecting hair fiber diameter.
41 citations
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December 2019 in “Stem Cell Reviews and Reports” This review discusses the progress in tooth regeneration research and highlights the potential of spatial-temporal release of developmental factors, but it reports no new clinical findings.
3 citations
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January 2017 in “Stem Cells International” This article highlights the significant challenge that tissue regeneration presents to modern medicine, emphasizing its importance in improving quality of life.
September 2025 in “Jinekoloji-Obstetrik ve Neonatoloji Tıp Dergisi” This review explores how fluctuations in female sex steroid hormone levels affect periodontal health in women, noting that collaboration between dentists and gynecologists may improve diagnosis and treatment of hormone-related periodontal conditions.
January 2024 in “Wiadomości Lekarskie” This research discusses the author's findings on methods for harvesting and preparing fat tissue for transplantation, highlighting rare but serious complications reported in animal studies and the use of conditioning devices.