Development of Growth Factor-Incorporating Liposomes for Integration Into Scaffolds as a Method to Improve Tissue Regeneration

September 2021 in “ The International Journal of Developmental Biology ”

Evangelos Natsaridis, Panagiota Mouzoura, Foteini Gkartziou, A. Marazioti, Sophia G. Antimisiaris

growth factors liposomes tissue regeneration liposomal drug delivery systems

Studysummary This review updates on the development of liposomal carriers for delivering growth factors to improve tissue regeneration and highlights recent efforts to enhance their stability and retention in tissues.

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Skin-Permeable Liposome Improved Stability and Permeability of bFGF Against Skin of Mice With Deep Second-Degree Scald to Promote Hair Follicle Neogenesis Through Inhibition of Scar Formation

research Skin-Permeable Liposome Improved Stability and Permeability of bFGF Against Skin of Mice With Deep Second-Degree Scald to Promote Hair Follicle Neogenesis Through Inhibition of Scar Formation

26 citations , September 2018 in “Colloids and Surfaces B: Biointerfaces”

This study reported that a novel liposomal formulation, SP-bFGF-SF-LIP, enhanced bFGF stability and skin permeability, significantly improving hair follicle recovery and wound healing in a mouse model.

research Augmenting Endogenous Wnt Signaling Improves Skin Wound Healing

61 citations , October 2013 in “PLoS ONE”

This study found that amplifying Wnt signaling, either genetically or through topical application of liposomal Wnt3a, improved skin wound healing in a mouse model.