Cytotoxicity and Collagen Expression Effects of Tideglusib Administration on Human Periodontal Cells: An In-Vitro Study

    May 2020 in “ Clinical and Experimental Health Sciences ”
    Buse ONCU, Ayşe Mine Yılmaz, Betül Karademir … Ömer Birkan Ağralı
    Studysummary This study found that Tideglusib at 50nM stimulated Type-I collagen production in human gingival fibroblasts and osteoblasts, suggesting potential benefits for bone regeneration.
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    Research cited in this study 3

    1. Wnt Signaling and Injury Repair Cold Spring Harbor Perspectives in Biology · 2012
    2. Bone Regeneration Is Regulated by Wnt Signaling Journal of Bone and Mineral Research · 2007
    3. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007