research The Hair Follicle as an Estrogen Target and Source
Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
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research Overview of Common, Rare, and Atypical Manifestations of Cutaneous Lupus Erythematosus and Histopathological Correlates
The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.
research Skin CD4+ Memory T Cells Exhibit Combined Cluster-Mediated Retention and Equilibration with the Circulation
Memory T cells in the skin balance staying put and moving into the blood, clustering around hair follicles, and increasing in number after infection.
research Alopecia Areata: Overview and Treatment Options
Alopecia areata causes hair loss, has no cure, and various treatments exist.
research The Pathogenesis of Primary Cicatricial Alopecias
The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.
research The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside
Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.
research Hair Regrowth
Finasteride and minoxidil are effective for hair regrowth, while treatments for alopecia areata have varying success and continuous treatment is necessary.
research In Vivo Immunological Toxicity in Mice of Carbon Nanotubes with Impurities
Pure carbon nanotubes are safe for mice, but impure ones cause immune issues and hair loss.
research Hair Follicle Immune Privilege Revisited: The Key to Alopecia Areata Management
Restoring hair bulb immune privilege is crucial for managing alopecia areata.
research Female Pattern Hair Loss: A Clinical and Pathophysiological Review
Female Pattern Hair Loss affects women's self-esteem and needs more research for better treatment.
research Trichoscopy of Alopecia Areata: An Update
Trichoscopy helps diagnose and monitor alopecia areata by looking at a combination of specific hair and scalp features.
research The Pathogenesis of Alopecia Areata
Alopecia areata is likely caused by a combination of genetic factors and immune system dysfunction, and may represent different diseases with various causes.
research Human αβ and γδ T Cells in Skin Immunity and Disease
Certain types of T cells are essential for healthy skin and play a role in skin diseases, but more research is needed to improve treatments.
research Alopecia Areata: Animal Models Illuminate Autoimmune Pathogenesis and Novel Immunotherapeutic Strategies
Animal models have helped understand hair loss from alopecia areata and find new treatments.
research Lichen Planopilaris and Frontal Fibrosing Alopecia as Model Epithelial Stem Cell Diseases
Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.
research What Causes Hidradenitis Suppurativa?—15 Years After
Hidradenitis suppurativa is caused by genetic factors, inflammation, bacteria, hormones, and lifestyle factors like obesity and smoking.
research Acne and Systemic Disease
Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.
research Mast Cell Deficient and Neurokinin-1 Receptor Knockout Mice Are Protected from Stress-Induced Hair Growth Inhibition
Certain mice without specific receptors or mast cells don't lose hair from stress.
research Cutaneous Lupus Erythematosus: A Comprehensive Review
The document concludes that skin biopsies, genetic and environmental factors, and specific treatments are important in managing cutaneous lupus erythematosus.
research Advanced Nanocarrier- and Microneedle-Based Transdermal Drug Delivery Strategies for Skin Diseases Treatment
Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
research Local Heroes or Villains: Tissue-Resident Memory T Cells in Human Health and Disease
Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.
research Stress-Related Skin Disorders
Stress can worsen skin conditions by affecting hormone levels and immune response.
research Neuronal Plasticity of the Brain-Skin Connection: Stress-Triggered Up-Regulation of Neuropeptides in Dorsal Root Ganglia and Skin via Nerve Growth Factor-Dependent Pathways
Stress increases certain chemicals in the skin and nerves, which might worsen skin conditions.
research Systematic Review of Platelet-Rich Plasma Use in Androgenetic Alopecia Compared with Minoxidil, Finasteride, and Adult Stem Cell-Based Therapy
PRP injections may be a safe, effective alternative for hair loss treatment compared to minoxidil and finasteride.
research The Role of Macrophages in Skin Homeostasis
Macrophages are vital for skin healing, hair growth, salt balance, and cancer defense.
research Transcriptional Profiling in Alopecia Areata Defines Immune and Cell Cycle Control Related Genes Within Disease-Specific Signatures
The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.
research The Role of Lymphocytes in the Development and Treatment of Alopecia Areata
Lymphocytes, especially CD8+ T cells, play a key role in causing alopecia areata, and targeting them may lead to new treatments.
research Unmet Medical Needs in Chronic, Non-Communicable Inflammatory Skin Diseases
There are still challenges in diagnosing and treating chronic skin diseases, but there is hope for future improvements.
research Functional Complexity of Hair Follicle Stem Cell Niche and Therapeutic Targeting of Niche Dysfunction for Hair Regeneration
Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.
research The C3H/HeJ Mouse and DEBR Rat Models for Alopecia Areata: Review of Preclinical Drug Screening Approaches and Results
Both mouse and rat models are effective for testing alopecia areata treatments.