March 2024 in “Journal of cosmetic dermatology” This study found that oral isotretinoin significantly reduced symptoms in nearly 90% of patients with frontal fibrosing alopecia, affecting both facial papules and hair loss.
1 citations
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April 2018 in “Dermatologic Surgery” This source outlines the scope and content of the Dermatologic Surgery journal, highlighting its focus on comprehensive peer-reviewed information related to various dermatologic surgeries, including cosmetic and reconstructive procedures and skin cancer treatment, as an essential resource for professionals in the field.
8 citations
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September 2011 in “European Journal of Dermatology” This study reports that most cases of frontal fibrosing alopecia did not show significant improvement with available treatments, and effective management remains unproven.
18 citations
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October 2019 in “Advanced Pharmaceutical Bulletin” This study found that finasteride microemulsions significantly increased skin permeability in vitro, highlighting the potential for enhanced delivery of this drug through the skin.
September 2024 in “Journal of the American Academy of Dermatology” This study found that phenoxyethanol is the most common contact allergen in over-the-counter hair loss products, but its role in the development or exacerbation of frontal fibrosing alopecia remains unclear.
May 2023 in “Reactions Weekly” January 2013 in “Reactions Weekly” 3 citations
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June 2011 in “Clinical Cosmetic and Investigational Dermatology”
4 citations
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January 2015 in “Journal of analytical & bioanalytical techniques” This study developed a rapid and sensitive method for determining finasteride concentrations in pharmaceuticals, with results comparable to those from the standard HPLC method.
7 citations
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July 2021 in “The Journal of Dermatology” This study in Asian females found that higher use of moisturizers and sunscreen among FFA patients may reflect appearance concerns rather than indicating a direct link to the disease mechanism.
2 citations
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June 2021 in “Sultan Qaboos University medical journal” This case report presents three sisters with familial frontal fibrosing alopecia, making it the 25th documented familial case, with treatment results observed in one sister.
This trial will compare the effectiveness of spironolactone to doxycycline for treating acne in adult females, potentially offering an alternative to antibiotics and isotretinoin.
1 citations
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February 2023 in “Russian Journal of Bioorganic Chemistry” In an animal study, researchers observed that a newly synthesized deoxycholic acid derivative showed similar prostate protection effects to finasteride in Wistar rats while being less toxic.
4 citations
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June 2017 in “Annales de dermatologie et de vénéréologie” This prospective study in Morocco reported on 20 cases of frontal fibrosing alopecia, finding that dermoscopy played a key role in diagnosing and managing the condition, which can increasingly affect premenopausal women.
January 2026 in “Journal of Applied Polymer Science” In this study, researchers developed a novel composite fiber by incorporating minoxidil sulfate-loaded ZIF-8 nanoparticles into a polyvinyl alcohol matrix, achieving sustained drug release for up to 220 hours, strong mechanical properties, and the capability for cosmetic applications like wigs.
17 citations
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June 1996 in “The Journal of Steroid Biochemistry and Molecular Biology” In this study, FCE 28260 showed greater potency than finasteride in inhibiting 5α-reductase enzymes and reducing prostate DHT levels in rats.
January 2009 in “Yaowu fenxi zazhi” This study established a reliable method for determining residual solvents in Finasteride using gas chromatography.
111 citations
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August 2002 in “Journal of Medicinal Chemistry” This study reports that 2-(1-Adamantyl)-4H-thiochromen-4-on-6-O-sulfamate is the most potent steroid sulfatase inhibitor identified so far, exhibiting 170-fold higher activity than the lead compound estrone sulfamate.
3 citations
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November 2020 in “Clinical, Cosmetic and Investigational Dermatology” This review summarizes the current treatment modalities for frontal fibrosing alopecia and provides a practical guide for clinicians, but reports no new clinical results.
April 2025 in “Journal of Reproductive Healthcare and Medicine” This study confirmed that an injectable implant known as RISUG-PH™, when administered via the vas deferens, successfully delivers the drug Finasteride to the prostate in male rats for up to 28 days, suggesting a potential localized alternative to oral delivery methods.
823 citations
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February 1998 in “Analytical Chemistry” Method detects finasteride in plasma at very low concentrations.
This study investigates whether adding 30% supramolecular salicylic acid to conventional treatment for mild to moderate acne vulgaris is safe and effective, though specific results are not reported in the abstract.
1 citations
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January 2024 in “Journal of molecular structure” This study developed a new finasteride release system using chitosan-based nanoniosomes, observing that 70% of the drug was released over ten days in vitro, suggesting potential for prostate cancer prevention.
23 citations
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April 2021 in “Journal of Clinical Medicine” This review compiles existing data on frontal fibrosing alopecia and highlights the promise of 5-alpha reductase inhibitors as a treatment option, while noting the need for clarity on its cause and progression.
21 citations
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January 2008 in “Talanta” New, cheaper method measures finasteride in tablets accurately and quickly.
16 citations
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January 2007 in “Actas dermo-sifiliográficas/Actas dermo-sifiliográficas” This review discusses frontal fibrosing alopecia and reports no clinical results; the authors note that no therapeutic options tested, including corticosteroids, finasteride, and minoxidil, have shown clear benefits.
25 citations
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October 2008 in “Chromatographia” This study developed and validated a sensitive and rapid method to simultaneously measure alfuzosin and dutasteride in human plasma, enabling high-throughput analysis for pharmacokinetic and bioequivalence studies.
3 citations
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November 2017 in “International Journal of Pharmacy and Pharmaceutical Sciences” This study identified new oxidative derivatives of finasteride, including a newly discovered metabolite, by using the fungus Macrophomina phaseolina.
11 citations
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February 2025 in “Journal of Science Advanced Materials and Devices” This study reported that nanofibrous scaffolds made from a PVA and flaxseed extract combination showed enhanced antimicrobial activity and significantly better wound healing in vitro compared to pure PVA fibers.
December 2021 in “Research Square (Research Square)” This study found that repeatedly collecting hair follicles from individuals with fragile X syndrome is feasible for measuring FMR1 and FMRP levels in both home and office settings.