Frontal Fibrosing Alopecia: Prospective Study of 20 Cases

    Sara Elloudi, S. Gallouj, Mariame Meziane, Mernissi FZ, M. Rimani
    TLDR The study found that a specific type of hair loss is increasingly common in premenopausal women and can be effectively diagnosed and treated with various medications.
    This prospective study examined 20 cases of frontal fibrosing alopecia (FFA) over 16 months at the dermatology department of Hassan II University in Fez, Morocco. All patients were women with an average age of 46 years, and 65% were premenopausal. Dermoscopic examination revealed specific signs of FFA, and skin biopsies confirmed the diagnosis. Half of the patients had immune dysfunctions or other disorders. Treatments included topical corticosteroids, tacrolimus ointment, minoxidil 2%, hydroxychloroquine, and oral finasteride, with satisfactory results observed within one year. The study concluded that FFA is increasingly common in premenopausal women and that dermoscopy is valuable for diagnosis, guiding biopsies, evaluating treatment efficacy, and establishing prognosis.
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      in Research  692 upvotes 4 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community 9 months on Fin - no progress , should I get on Dutasteride?

      in Chat  10 upvotes 1 month ago
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      community Testosterone and hair loss seeming irrelevance

      in Research/Science  81 upvotes 1 year ago
      The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

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      in Styling  72 upvotes 1 year ago
      A 25-year-old with AGA experienced hair thinning and dandruff, stabilized with topical finasteride and minoxidil but saw minimal regrowth. They seek advice on styling and consider oral minoxidil and microneedling for denser hair.

      community scarring alopecia awareness in this community

      in Chat  33 upvotes 2 years ago
      Lichen Planopilaris (LPP), a form of permanent hair loss, which can be mistaken for seborrheic dermatitis and is characterized by scalp itching, burning, redness, and dandruff. Treatment options discussed include steroidal creams, finasteride, minoxidil, and RU58841.

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