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Glossary Immune Dysfunction

immune system fails to protect the body properly

Immune Dysfunction, also known as Immune System Disorder, refers to a condition where the immune system does not function properly. This can manifest as an overactive immune response, leading to autoimmune diseases where the body attacks its own tissues, or an underactive response, resulting in immunodeficiency where the body is unable to effectively fight off infections. Examples include conditions like rheumatoid arthritis (autoimmune) and HIV/AIDS (immunodeficiency).

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Research

5 / 1000+ results

The Interplay of Oxidative Stress and Immune Dysfunction in Hashimoto’s Thyroiditis and Polycystic Ovary Syndrome: A Comprehensive Review

research The interplay of oxidative stress and immune dysfunction in Hashimoto’s thyroiditis and polycystic ovary syndrome: a comprehensive review

1 citations , July 2023 in “Frontiers in Immunology”

This review highlights the role of chronic stress, oxidative stress, and immune processes in the development of Hashimoto’s thyroiditis and polycystic ovary syndrome, emphasizing the potential of antioxidants in their treatment based on the existing literature.

research 1368 Does mitochondrial dysfunction drive immune privilege collapse in lichen planopilaris pathogenesis?

April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

This study suggests that mitochondrial dysfunction might contribute to the pathogenesis of Lichen planopilaris by triggering a metabolic shift that leads to chronic inflammation and hair follicle damage.

research Hidradenitis suppurativa: A folliculotropic disease of innate immune barrier dysfunction?

9 citations , August 2021 in “Experimental dermatology”

This review examines the dysregulation of innate immune barriers in the early stages of hidradenitis suppurativa and calls for further research on the role of the hair follicle and immune responses, but reports no new results.

research Clinical Application of Development of Nonantibiotic Macrolides That Correct Inflammation-Driven Immune Dysfunction in Inflammatory Skin Diseases

22 citations , January 2012 in “Mediators of inflammation”

This review discusses the potential benefits of nonantibiotic macrolides for treating inflammatory skin disorders and reports no new clinical results.

research Unraveling Vitiligo: From Immune Mechanisms to Promising Therapeutic Strategies

December 2024 in “Journal of Clinical Medicine of Kazakhstan”

This review highlights the potential of combining immune regulation, phototherapy, and dietary strategies for effective vitiligo treatment, but emphasizes that more research is needed.

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Community Join

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community Why is Finasteride seen as “scary” for men, but hormonal birth control is totally normalized for women?

in Finasteride/Dutasteride 757 upvotes 1 year ago

Finasteride is seen as risky for men due to side effects like erectile dysfunction, while hormonal birth control for women is normalized despite its side effects. The discussion points out a double standard influenced by societal and gender norms.

community How is dht not beneficial to you?

in Finasteride/Dutasteride 111 upvotes 7 months ago

DHT is important for sexual function and mood, but finasteride and dutasteride can reduce DHT, causing side effects like reduced libido and erectile dysfunction. These treatments are effective for hair loss, but their impact on DHT leads to debate.

community Finasteride does deplete important nuero-active steroids

11 upvotes 3 years ago

Finasteride can reduce neuroactive steroids, causing side effects like depression, anxiety, and sexual dysfunction. Some users experience persistent symptoms after stopping finasteride, while others use alternative treatments like topical solutions.

community Rubedo Life Sciences Announces Clinical Study to Treat Hair Loss with GPX4 Modulator RLS-1496, First Human Ex Vivo Evidence Demonstrates Robust Hair Follicle Growth

1071 upvotes 6 days ago

Rubedo Life Sciences is developing a GPX4 modulator, RLS-1496, for hair loss treatment, showing promising hair follicle growth in early tests. Concerns include potential side effects like organ damage, with a realistic market release several years away.

community My Theory Of Androgenic Alopecia

16 upvotes 10 months ago

Hair loss is linked to cellular physiology and the IGF-1 to TGF-B1 ratio, not just androgen sensitivity. The theory lacks evidence, while finasteride and minoxidil are effective treatments.

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Learn

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learn zinc PCA

Is it possible to take too much zinc when using hair supplements, and what are the risks? Excessive zinc intake can lead to health issues like nausea, headaches, and immune dysfunction.

learn Osteopontin

signaling protein that, when suppressed, may grow hair by reducing inflammation and stem cell loss

learn procapil

Tried everything and still getting bald patches? Procapil may help calm the immune response Procapil is a cosmetic ingredient complex; laboratory studies of its individual ingredients report anti-inflammatory effects, but no published clinical trial has tested it in alopecia areata or any other immune-related hair loss. Spreading bald patches should be assessed by a dermatologist.

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