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January 2002 The document reviewed key clinical trials related to the treatment of benign prostatic hyperplasia (BPH), focusing on various medications and their long-term efficacy. It covered the use of alpha-blockers like Terazosin, Doxazosin, and Alfuzosin, highlighting their effectiveness in managing BPH symptoms. Finasteride was examined for its long-term benefits, including its impact on reducing acute urinary retention and the need for surgical intervention over several years. The trials also compared the effectiveness of these medications, both individually and in combination, against placebo and other treatments like phytotherapy and transurethral surgery. The studies provided insights into the management of BPH symptoms, considering factors such as patient blood pressure and the placebo effect.