15 citations
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January 2017 in “Experimental Neurology” This study found that finasteride significantly reduced levodopa-induced dyskinesia in both male and female rats without diminishing l-DOPA's motor benefits, indicating potential for clinical trials in Parkinson's patients.
12 citations
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November 2003 in “Journal of the American Academy of Dermatology” This study found hair regrowth in the majority of AA-affected mice and rats treated with diphencyprone, suggesting its potential utility for understanding human alopecia areata and the drug's therapeutic action.
43 citations
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August 2010 in “Expert Opinion on Investigational Drugs” This review explores the potential of selective 11β-HSD1 inhibitors to improve insulin sensitivity in type 2 diabetes, emphasizing the need for more clinical research and reports no new clinical results.
3 citations
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August 2022 in “Pharmaceuticals” This study observed that a self-emulsifying drug delivery system for finasteride significantly enhanced bioavailability in rats compared to commercial tablets, but the formulation was found to be thermodynamically unstable.
January 2026 in “AIMS Public Health” This abstract describes the approval of a study by the Japan Registry of Clinical Trials and the North South University Institutional Review Board, but it does not report any results or conclusions.
April 2018 in “The Journal of Urology” This study found that phosphodiesterase inhibitors may suppress the proliferation of benign prostatic hyperplasia epithelial cells by modulating CCL5 levels in low androgen conditions.
18 citations
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December 2016 in “European journal of pharmacology” In this study, 12-Chloracetyl-PPD showed anti-cancer activity by inhibiting cancer cell viability and inducing apoptosis through reactive oxygen species production without harming normal cells.
This abstract details known indications, categories, and potential reactions for various drugs, including anorexiants, estrogens, NSAID analgesics, cardiac glycosides, and migraine preventives, without reporting new clinical results.
June 2026 in “Precision medicine and engineering.” In this study, researchers created a hydrogel that reduces oxidative stress and releases a pro-angiogenic drug in response to enzyme activity, which accelerated healing and improved tissue regeneration in chronic diabetic wounds during in vivo experiments.
This review discusses recent advances in polydopamine-based biomaterials and their growing potential in personalized medicine, but reports no new experimental results; the authors highlight both opportunities and challenges for future applications.
62 citations
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November 2022 in “Acta Pharmaceutica Sinica B” This study reported that an injectable hydrogel based on platelet-rich plasma and laponite improved wound healing in diabetic and normal rats by enhancing angiogenesis and macrophage polarization.
12 citations
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February 2013 in “The Open Stem Cell Journal” This article reviews the definitions, opportunities, advantages, and limitations of dental pulp stem cells and stem cells from human exfoliated deciduous teeth in tissue engineering and regenerative medicine, reporting no new clinical results.
June 2023 in “Clinical Cosmetic and Investigational Dermatology” This report describes a 60-year-old female with pretibial pruritic papular dermatitis who showed significant improvement of skin lesions after one month of treatment with oral pentoxifylline. The authors highlight the unique clinical and histological features of PPPD and propose pentoxifylline as a potential therapy.
January 2024 in “Medicinska istrazivanja” This case report describes erosive pustular dermatosis of the scalp in a 55-year-old woman, which improved rapidly with oral antibiotics and topical corticosteroids but resulted in permanent scarring alopecia, emphasizing the need for prompt diagnosis and treatment to minimize scarring.
June 2024 in “Lasers in Surgery and Medicine” This study found that the novel dermal cooling system was an effective and safe treatment for reducing pigmentation in benign pigmented lesions in Asian patients, with minimal side effects.
1 citations
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November 2025 in “Clinical Chemistry and Laboratory Medicine (CCLM)” This study developed a new measurement procedure using isotope dilution-liquid chromatography-tandem mass spectrometry for accurate quantification of DHEAS in human serum or plasma, demonstrating high selectivity, sensitivity, and low measurement uncertainty, making it suitable for routine standardization and clinical evaluation.
3 citations
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November 2021 in “Skin Appendage Disorders” This study found that home-use diphenylcyclopropenone (H-DPCP) is a cost-effective alternative to office-use for severe alopecia areata, showing similar effectiveness with reduced costs.
August 2025 in “International Journal of Environmental Sciences” In this descriptive cross-sectional study, researchers observed that less than 10% of female nursing students in Dharmapuri have been diagnosed with polycystic ovarian syndrome, though many show increasing symptom prevalence and poor health-related behaviors, underlining the need for better education and regular gynecological check-ups.
May 2024 in “Journal of the Egyptian Womenʼs Dermatologic Society” This study suggests that DPCP treatment can be effective and safe for severe alopecia areata in children, with maintenance therapy potentially reducing relapse rates.
1 citations
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August 2021 This study found that biomimetic dermal papilla spheres cultured in a specific microenvironment can partially restore hair-inducing ability in high-passage dermal papilla cells in nude mice, resembling the characteristics of primary cells.
26 citations
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September 2018 in “Neurobiology of Disease” This study found that both finasteride and dutasteride significantly reduced L-DOPA-induced dyskinesia in a rat model of Parkinson's disease, with dutasteride showing greater effectiveness at lower doses.
September 2023 in “Journal of the American Academy of Dermatology” Recognizing IPPP is crucial to prevent misdiagnosis and unnecessary treatments.
37 citations
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September 2009 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This study found that diphencyprone is an effective and safe treatment for extensive alopecia areata, especially with long-term therapy and maintenance to reduce relapse risk.
2 citations
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March 2016 in “The Journal of Urology” This study found that the 1 mg dose of finasteride was associated with a wide range of adverse effects, including sexual, psychological, and metabolic symptoms, in the FAERS data.
1 citations
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April 2019 in “Journal of Investigative Dermatology” This study examined the safety and efficacy of dupilumab in adolescents with moderate-to-severe atopic dermatitis, finding that it was well tolerated and significantly improved symptoms over 52 weeks, with its safety profile similar to that in adults.
September 2021 in “Physiology News” This abstract appears to consist entirely of repeated color specifications and logo guidelines, providing no research findings or new results.
9 citations
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February 2012 in “Clinical Neurology and Neurosurgery” In this paper, three APS patients were followed over time, showing that the diagnosis and course of autoimmune polyglandular syndrome can evolve, highlighting the need for careful monitoring and potential re-evaluation.
34 citations
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February 2016 in “Fertility and Sterility” This study suggests that higher PDCD4 expression may play a significant role in polycystic ovary syndrome pathogenesis through its association with obesity, insulin resistance, lipid metabolism disorders, and increased granulosa cell apoptosis.
86 citations
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March 2018 in “ACS Biomaterials Science & Engineering” This study found that MDP hydrogel significantly accelerated wound healing and improved tissue formation in diabetic mice compared to a standard clinical hydrogel and control buffer.
57 citations
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February 2014 in “Experimental Dermatology” This review discusses the role of Prostaglandin D2 and its synthase in androgenetic alopecia but reports no new clinical findings, suggesting pathways for future therapeutic development.