Five-Year Experience in the Treatment of Alopecia Areata with Diphencyprone
TLDR Diphencyprone (DPC) is an effective and safe long-term treatment for alopecia areata, especially with maintenance therapy.
The study evaluated the effectiveness of Diphencyprone (DPC) in treating alopecia areata (AA) over five years, involving 135 patients divided into groups based on the extent of scalp affection. Results showed that 55.7% of patients achieved an excellent response (terminal hair covering >75% of the scalp) after 24 months, with the highest success in patients with less extensive AA. Maintenance therapy significantly reduced relapse rates, with 17.9% experiencing >25% hair loss compared to 57.1% without maintenance. The study concluded that DPC is an effective and safe treatment for extensive AA, recommending long-term and maintenance therapy to enhance outcomes and reduce relapse risk.
