Pretibial Pruritic Papular Dermatitis: A Case Report and Emphasis on Effective Treatment with Pentoxifylline

June 2023 in “ Clinical Cosmetic and Investigational Dermatology ”

Nawara Sakpuwadol, Sarawin Harnchoowong, Poonkiat Suchonwanit

pretibial pruritic papular dermatitis pruritic papules plaques pentoxifylline

TLDR Pentoxifylline effectively improves pretibial pruritic papular dermatitis.

Pretibial pruritic papular dermatitis (PPPD) is a rare skin disorder characterized by pruritic papules and plaques on the pretibial area, often resulting from chronic manipulation. This case report discusses a 60-year-old female with PPPD who experienced significant improvement in her lesions after 1 month of treatment with oral pentoxifylline. The report highlights the unique clinical and histological features of PPPD and suggests pentoxifylline as a novel and effective treatment option for this underrecognized condition.

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