An Isotope Dilution-Liquid Chromatography-Tandem Mass Spectrometry-Based Candidate Reference Measurement Procedure for the Quantification of Dehydroepiandrosterone Sulfate in Human Serum and Plasma

    November 2025 in “ Clinical Chemistry and Laboratory Medicine (CCLM) ”
    Sara Cheikh Ibrahim, N. S. Singh, Katrin Gradl … Judith Taibon
    Studysummary This study developed a new measurement procedure using isotope dilution-liquid chromatography-tandem mass spectrometry for accurate quantification of DHEAS in human serum or plasma, demonstrating high selectivity, sensitivity, and low measurement uncertainty, making it suitable for routine standardization and clinical evaluation.
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    Research cited in this study 2

    1. Congenital Adrenal Hyperplasia: Comprehensive Overview and Clinical Management Journal of Pediatric and Adolescent Gynecology · 2011
    2. Is Dehydroepiandrosterone a Hormone? Journal of Endocrinology · 2005