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This study found that methylcellulose-based hydrogels can effectively deliver growth hormone through the skin, with albumin increasing the hormone's permeation to 93% in simulated in vivo conditions.

In this study, researchers identified that keloid fibroblasts respond to neurotransmitters from catecholaminergic nerves by producing bone matrix proteins, mediated by β1-adrenergic receptor activation, leading to fibro-osseous reprogramming; blocking this signaling in a rodent model prevented the development of keloid-like pathology.

In this study, cell membrane remodeling with a thermoresponsive boronic acid copolymer was shown to rapidly form spheroids from cancer or cardiac cell lines under standard conditions, promising advances in tissue engineering.

This study found that the BIK1 gene in Arabidopsis thaliana modulates defense responses to pathogens and is essential for normal root growth and development.

This study evaluated nanovesicles derived from Polygonum multiflorum roots, finding that they promote dermal papilla cell proliferation and activate β-catenin signaling, which in turn enhances hair shaft elongation in ex vivo cultured human hair follicles, suggesting their potential use for alopecia treatment.

In this study, the vitamin D analogues 1 alpha,25-dihydroxy-vitamin D3 and calcipotriol were found to thin the living cell layer and affect differentiation marker expression in organotypic cultures of human outer root sheath cells.

In this study, a subcutaneous injection of recombinant RSPO1 was found to activate hair follicle stem cells and enhance hair regeneration in mice by stimulating the Wnt/β-catenin signaling pathway, suggesting its potential as a treatment for hair loss.

This study synthesized a temperature-sensitive hydrogel with strong antibacterial capabilities against S. aureus and E. coli, demonstrated via in vitro and in vivo tests, suggesting potential for antibiotic-free clinical applications when activated by near-infrared light.

This study found that a thyroid hormone receptor ẞ subtype-selective thyromimetic was effective in promoting hair growth in mouse and monkey models when applied topically.

This study indicates that a helminth-derived protein, TGF-β mimic, may accelerate wound healing and promote regenerative processes in skin tissue by interacting with TGF-β receptors.

In this study, researchers differentiated induced pluripotent stem cells into cells with dermal papilla-like properties, demonstrating their potential role in hair follicle bioengineering and drug testing for hair growth.

In this study, injectable platelet-rich fibrin (i-PRF) was found to enhance the proliferative, migratory, and hair-inducing abilities of dermal papilla cells more effectively than platelet-rich plasma through the TGF-β/Smad pathway.

This study found that sphingosine 1-phosphate and its receptor S1PR3 are essential in regulating the acute mechanical pain response, highlighting their role in mechanonociception without affecting responses to innocuous touch or thermal stimuli.

This study found that platelet-derived extracellular vesicles from apheresis platelets may effectively activate dermal papilla cells and promote hair follicle growth in a mouse model of hair regeneration.

According to this study, human scalp hair follicles containing pluripotent stem cells demonstrated the ability to differentiate into cardiac muscle cells and other cell types, suggesting potential applications in heart and nerve regeneration.

This study evaluated the phytochemical properties and in-vitro anti-fungal activity of Tridax procumbens but reports no new clinical results.

This study found that BMP2 increased PTEN expression and induced autophagy, promoting hair follicle stem cell differentiation in both in vitro models and a mouse wound model.

Natural products can safely and effectively treat various human diseases.

This study found that corticotropin-releasing factor influences cytokine expression related to hair growth in human dermal papilla cells and suggests CRF receptor antagonists could be potential treatments for stress-induced hair loss.

This review evaluates controlled studies on Platelet-Rich Plasma for androgenetic alopecia treatment, reporting positive effects on hair growth and density but highlighting the need for standardized protocols.

Certain tyrosine kinases may regulate hair growth and could help develop hair loss treatments.

This study found that pregnane derivatives with higher lipophilicity, like compound 9d, had stronger androgen receptor binding and greater antiandrogenic effects in rats, correlating relative binding affinity with log P values.

This study found that brain-derived neurotrophic factor (BDNF) inhibited hair shaft elongation and induced premature catagen development in cultured human hair follicles, partially through transforming growth factor β2.

This source reports on advances in stimulus-responsive nanoparticle-based PROTACs (nano-PROTACs), which aim to overcome existing challenges like poor cell permeability and systemic off-target effects by enabling controlled protein degradation through endogenous or exogenous stimuli, potentially enhancing therapeutic efficacy and reducing toxicity.

This study found that targeting HSP70 can suppress basal cell carcinoma growth, underscoring the importance of tumor microenvironment interactions in cancer progression.

This study found that 4-aminopyridine significantly improves skin wound healing by enhancing various cellular and molecular processes, suggesting its potential for rapid translational development in wound treatment.

This study found that bursts of ERK activation in the epidermis of mice were linked to cell division, supporting synchronized cell proliferation and transient ERK activity in living tissues.

This study identifies substance P, TNFα, and IFNγ as novel regulators of prolactin and its receptor expression in human skin, suggesting intracutaneous prolactin is not controlled by dopamine.

In this study, researchers found that thrombin may influence cyclic hair growth through its receptor PAR-1, although it does not seem to stimulate dermal papilla cell proliferation physiologically.