4-Aminopyridine Promotes Accelerated Skin Wound Healing

    November 2021 in “ Research Square (Research Square) ”
    Mashanipalya G. Jagadeeshaprasad, Prem Kumar Govindappa, Amanda M. Nelson … John C. Elfar

    Preprint — not peer reviewed. This was posted to a preprint server or data repository. It has not been through a journal's review process, and its findings may change or not hold up.

    Studysummary This study found that 4-aminopyridine significantly improves skin wound healing by enhancing various cellular and molecular processes, suggesting its potential for rapid translational development in wound treatment.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 8

    1. Sensory Reinnervation of Human Skin by Human Neural Stem Cell-Derived Peripheral Neurons Ex Vivo ˜The œjournal of investigative dermatology/Journal of investigative dermatology · 2021
    2. Cell Types Promoting Goosebumps Form a Niche to Regulate Hair Follicle Stem Cells Cell · 2020
    3. Epidermal Stem Cells in Wound Healing and Regeneration Stem Cells International · 2020
    4. Epidermal Stem Cells in Wound Healing and Their Clinical Applications Stem Cell Research & Therapy · 2019
    5. Immunological Challenges Associated With Artificial Skin Grafts: Available Solutions and Stem Cells in Future Design of Synthetic Skin Journal of Biological Engineering · 2017
    6. dsRNA Released by Tissue Damage Activates TLR3 to Drive Skin Regeneration Cell Stem Cell · 2015
    7. Keratin K15 as a Biomarker of Epidermal Stem Cells International Journal of Molecular Sciences · 2013
    8. Wnt-Dependent De Novo Hair Follicle Regeneration in Adult Mouse Skin After Wounding Nature · 2007