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Hair can regrow in large wounds through a process similar to how hair forms in embryos, and understanding this could lead to new treatments for hair loss or scarring.

Acne is caused by multiple factors including oil production, bacteria, inflammation, and possibly diet and environment.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Janus kinase inhibitors are promising treatments for autoimmune skin diseases like eczema and psoriasis.

Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.

Cell death shapes skin stem cell environments, affecting inflammation, repair, and cancer.

A substance called miR-1246 may help treat severe hair loss by reducing certain immune cell activities.

Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

Arsenic exposure from contaminated water severely damages the skin, causing hair loss, pigmentation changes, irritation, and can lead to skin cancer.

Human keratinocytes do not naturally respond to androgens.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Targeted cancer therapies often cause serious skin problems that need careful management.

The document provides advice on how to recognize and treat skin-related side effects of cancer drugs known as EGFR inhibitors.

The document concludes that Rabson-Mendenhall syndrome requires novel treatments for insulin resistance and emphasizes the importance of dental care in affected patients.

Dental pulp stem cells might not reliably become neurons.

Sebaceous glands can heal and regenerate after injury using their own stem cells and help from hair follicle cells.

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.

Testosterone may slow down wound healing and increase inflammation.

Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.

Tofacitinib may slow hair loss in scarring alopecias but is unlikely to regrow significant hair.

Skin problems are common in lupus, often appearing first, with various types and treatments, and careful monitoring is important for diagnosis and management.

The document is a detailed medical reference on skin and genetic disorders.

Oral tofacitinib can significantly improve recalcitrant lichen planopilaris.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

Activating Notch in adult skin causes T cells and neural crest cells to gather, leading to skin issues.