Correlation Between Biochemical and Clinical Hyperandrogenism Parameters in Polycystic Ovary Syndrome in Relation to Age

    April 2023 in “ BMC endocrine disorders ”
    Zaixin Guo, Fen Jin, Shuwen Chen, Pan Hu, Yanfang Hao, Qi Yu
    Image of study
    TLDR The link between physical signs of high male hormones and hormone levels in women with PCOS changes with age.
    This study examined the correlation between clinical and biochemical hyperandrogenism in 256 women with PCOS, divided into two age groups: 18-29 years and 30-40 years. Younger women showed a significant positive correlation between clinical hyperandrogenism (especially hirsutism) and the free androgen index (FAI), DHEA, and DHEA-S. In contrast, older women had clinical hyperandrogenism influenced more by DHEA, DHEA-S, and DHT, with no significant correlation for alopecia. The study concludes that the relationship between clinical and biochemical hyperandrogenism parameters varies with age, emphasizing the need for age-specific diagnostic and treatment strategies for PCOS.
    Discuss this study in the Community →

    Research cited in this study

    7 / 7 results

    Related Community Posts Join

    6 / 7 results

      community DHT levels after 4 weeks of Fina and 8 weeks of Fina + 4 weeks of Duta

      in Update  37 upvotes 6 years ago
      The user reported early stage diffuse hair thinning and increased DHT levels after 4 weeks on Finasteride and 8 weeks on Finasteride plus 4 weeks on Dutasteride, despite the medications being authentic and stored properly. They are considering increasing their Dutasteride dosage due to the lack of side effects and are unsure if the treatment is helping their hair.

      community Proposed new pathogenesis model for androgenetic alopecia (AGA)

      in Research/Science  8 upvotes 1 year ago
      The conversation discusses a new model for understanding androgenetic alopecia (AGA), linking it to dietary and lifestyle factors similar to PCOS, and highlighting the role of DHT, vascular damage, and inflammation. Treatments mentioned include Minoxidil, finasteride, and RU58841.

      community Spironolactine Update: 2 months (34, Female)

      in Female  22 upvotes 8 years ago
      A female user's experience using Spironolactone to treat Female Pattern Hair Loss (FPHL) and Androgenic Alopecia, as well as discussing the effectiveness of the drug at different dosages.

      community Quit vaping/smoking = 80% less loss

      in Research/Science  235 upvotes 1 year ago
      Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

    Related Research

    4 / 4 results