Deleting Smad4 and PTEN genes in mice causes rapid, invasive forestomach cancer.
4 citations,
August 2005 in “Archives of Dermatological Research” Higher p63 and CD34 levels found in specific scalp areas may affect hair loss progression.
4 citations,
September 2020 in “Andrologia” Oregano extract helps fix testis and sperm damage caused by finasteride.
60 citations,
May 2011 in “Endocrinology and Metabolism Clinics of North America” Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.
50 citations,
February 2018 in “Biomedicine & pharmacotherapy” Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.
56 citations,
March 2003 in “Journal of Investigative Dermatology” 17β-estradiol can reduce inflammation in the skin.
63 citations,
May 2011 in “Clinical cancer research” The topical inhibitor CUR61414 was not effective in treating basal cell carcinoma in human trials.
October 2012 in “Medical Hypotheses” Artemis dysfunction might cause hair loss through telomere shortening.
1 citations,
January 2020 in “Archives of Medical Research” Formononetin, found in red clover, may treat hair loss with fewer side effects.
25 citations,
November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
21 citations,
November 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” Telogen is an active phase with important biological processes, not a resting phase.
10 citations,
January 2013 in “Clinical and developmental immunology/Clinical & developmental immunology” The document concludes that systemic autoimmune diseases are complex, incurable, and require ongoing treatment and research.
149 citations,
July 2014 in “Cold Spring Harbor Perspectives in Medicine” The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.
May 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Loss of TET2 increases the risk of skin and oral cancer.
Deleting the MAD2L1 gene is tolerated in certain mouse cancer models.
November 2023 in “European heart journal” Finasteride improves heart function and balance in aging and obese male rats by reducing oxidative stress.
July 2016 in “Journal of Investigative Dermatology” R-spondin2 may help treat hair loss, gene differences could explain baldness, a peptide's regulation is linked to psoriasis, B-defensin gene copies may affect a skin condition's risk and severity, and potential markers and targets for alopecia areata were identified.
6 citations,
February 2022 in “The journal of neuroscience/The Journal of neuroscience” Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.
17 citations,
December 2013 in “Journal of Investigative Dermatology Symposium Proceedings” Bimatoprost is safe and effective for treating eyelash loss caused by chemotherapy.
1 citations,
September 2023 in “Journal of Investigative Dermatology” Melatonin may protect hair follicle cells from damage caused by a chemotherapy drug.
June 2023 in “JAAD Case Reports” A man had a rare skin cancer that looked like a bald spot.
January 2019 in “Springer eBooks” Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.
16 citations,
February 2019 in “Journal of Cellular and Molecular Medicine” Researchers created a rat model to study skin damage caused by radiation, which could help develop new treatments.
September 2018 in “Fertility and Sterility” High levels of testosterone and anti-Müllerian hormone before pregnancy are linked to a higher risk of newborns needing intensive care.
6 citations,
February 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” A new model using mice with human hair follicles helps better understand hair loss from chemotherapy.
10 citations,
December 2018 in “Medical Science Monitor” The MAPK/ERK pathway is crucial in controlling cell growth and death in finasteride-induced hypospadias.
3 citations,
November 2011 in “Small GTPases” Researchers found that hair follicle stem cells can become squamous cell carcinoma due to Ras activation, which could lead to new treatments.
77 citations,
March 2014 in “Cold Spring Harbor Perspectives in Medicine” Fat cells are important for healthy skin, hair growth, and healing, and changes in these cells can affect skin conditions and aging.
3 citations,
September 2022 in “Molecules” Camellia seed cake extract may help hair growth by blocking the hair loss effects of a hormone called DHT.
January 2008 in “US endocrinology” Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.