33 citations,
April 2020 in “Journal of Clinical Investigation” Stress in hair follicle stem cells causes inflammation in a chronic skin condition through a specific immune response pathway.
33 citations,
January 1997 in “Endocrinology” Testosterone can slow down hair growth when combined with certain cells from bald scalps, and this effect can be blocked by an androgen receptor blocker.
29 citations,
July 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” The enzymes Aldh1a2 and Aldh1a3 are involved in making retinoic acid in hair follicles and have different roles in hair growth.
27 citations,
January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” Somatostatin may help protect hair follicles from immune attacks.
25 citations,
September 2018 in “Scientific Reports” Morroniside may help hair grow and stay in its growth phase by affecting certain cell signals.
25 citations,
July 1994 in “Journal of dermatological science” Testosterone affects hair follicles differently across body sites, with beard hair follicles showing more activity of a specific enzyme and presence of androgen receptors compared to scalp hair.
23 citations,
January 2018 in “BMC genomics” Vimentin is involved in regulating the hair growth cycle in Inner Mongolian Cashmere goats.
22 citations,
November 2013 in “Clinical and experimental dermatology (Print)” Ecklonia cava, a type of seaweed, may help hair grow.
21 citations,
April 2018 in “Journal of Dermatological Science” Cilostazol helps hair grow by making hair root cells grow faster and changing growth factor levels.
15 citations,
August 2017 in “International Journal of Molecular Medicine” Panax ginseng extract may help prevent hair loss caused by DKK-1.
15 citations,
September 2012 in “PTR. Phytotherapy research/Phytotherapy research” Ginsenosides Rb₁ and Rd may help prevent hair loss by promoting hair cell growth.
14 citations,
January 2009 in “Experimental Dermatology” Hair sheds gradually from the follicle, with readiness to shed indicated by less attachment material.
11 citations,
May 2016 in “Naunyn-Schmiedeberg's Archives of Pharmacology” A substance called 15-deoxy prostaglandin J2 can cause hair follicle cells to die, which might explain how prostaglandin D2 can lead to hair loss.
11 citations,
January 2012 in “Journal of cell science” Rac1 is essential for proper hair structure and color.
10 citations,
August 2018 in “Experimental Dermatology” Decorin helps hair cells grow and move, and keeps hair growth phase going in mice.
9 citations,
January 2008 in “Acta histochemica et cytochemica” COX-2 levels change during the hair cycle and affect skin and hair growth.
8 citations,
January 2012 in “International journal of polymer analysis and characterization/IJPAC. International journal of polymer analysis and characterization/IJPAC. International journal of analysis and characterization” Hydrogenated palm oil repairs and conditions damaged hair by preventing swelling.
7 citations,
November 2022 in “Communications biology” Keratin injections can promote hair growth by affecting hair-forming cells and tissue development.
6 citations,
April 1996 in “Journal of histochemistry and cytochemistry/The journal of histochemistry and cytochemistry” TGF-alpha is present in sheep and ferret skin and may affect hair growth without directly stimulating cell proliferation.
5 citations,
October 2020 in “Frontiers in Cell and Developmental Biology” Reducing FOXA2 in skin cells lowers their ability to grow hair.
5 citations,
January 2009 in “Dermato-endocrinology” ADAM 10 and ADAM 12 proteins are involved in different stages of hair growth and could be targets for treating hair disorders.
4 citations,
July 2022 in “Annals of translational medicine” Scientists created complete hair-like structures by growing mouse skin cells together in a special gel.
4 citations,
June 2022 in “Journal of Cosmetic Dermatology” Multi-peptide factors from fibroblasts may stimulate hair growth by increasing growth factors and β-catenin in hair cells.
4 citations,
March 2019 in “Experimental Biology and Medicine” Exposure to 50 Hz electromagnetic fields may help mice grow hair faster.
3 citations,
August 2020 in “International Journal of Molecular Sciences” Blocking Rab27a slows hair growth, while blocking Rab27b encourages it.
2 citations,
January 2022 in “International Journal of Medical Sciences” Kartogenin may help treat hair loss by promoting hair growth and extending the hair growth phase.
2 citations,
February 2019 in “Journal of Investigative Dermatology” Higher levels of the DP2 receptor may lead to hair loss.
2 citations,
March 2011 in “Veterinary Dermatology” FGF18 is present in beagle dog hair follicles, mainly in the inner root sheath.
1 citations,
August 2022 in “International Journal of Molecular Sciences” FGF12 is important for hair growth and could be targeted for hair loss treatment.
1 citations,
June 2006 in “Experimental dermatology” The conclusion suggests that early signs of hidradenitis suppurativa may start in the hair follicle, with genetic and immune factors playing a role, highlighting the need for more research on the hair follicle's immune system.