TLDR FGF18 is present in beagle dog hair follicles, mainly in the inner root sheath.
The study investigated the presence and localization of fibroblast growth factor 18 (FGF18) in the hair follicles of 10 healthy beagle dogs. Researchers aimed to determine if FGF18 played a role in hair follicle cycling, similar to findings in mice. Skin biopsies were taken from the shoulder and flank of the dogs in both winter and summer, and FGF18 was detected primarily in the inner root sheath of hair follicles, with some presence in the outer root sheath, dermal papilla, apocrine glands, arrector pili muscles, and vascular endothelial cells. The study found no significant differences in FGF18-positive cells or follicles based on sex, anatomical location, season, or sampling days.
61 citations,
September 2010 in “Genomics” The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.
45 citations,
December 2009 in “Veterinary dermatology” The book is recommended for its new scientific information and balanced treatment options for hair loss in domestic animals.
375 citations,
February 2006 in “Journal of Cell Science” The document concludes that the hair cycle is a complex process involving growth, regression, and rest phases, regulated by various molecular signals.
109 citations,
December 1998 in “The Journal of Dermatology” Manipulating the catagen and telogen phases of hair growth could lead to treatments for hair disorders.
56 citations,
July 2005 in “Experimental Dermatology” Injected human hair follicle cells can create new, small hair follicles in skin cultures.
January 2003 in “Chinese Journal of Reparative and Reconstructive Surgery” Dermal papilla cells can help form hair follicles and produce hair.
61 citations,
October 1996 in “Development” Hair growth can be stimulated by combining certain skin cells, which can rejuvenate old cells and cause them to specialize in hair follicle creation.
94 citations,
February 1994 in “The journal of investigative dermatology/Journal of investigative dermatology” EGF makes hair follicles grow longer but stops hair production.
