56 citations
,
April 2015 in “American journal of medical genetics. Part A” This study reports on eight previously unpublished cases of Bohring-Opitz syndrome with ASXL1 mutations, suggesting the importance of screening for Wilms tumors in these patients.
51 citations
,
March 2019 in “Journal of cellular physiology” This review discusses the use of platelet lysate and its growth factors in treating diseases and regenerative medicine but reports no new clinical findings.
47 citations
,
July 2013 in “Pharmacological Reviews” This review discusses the role of pharmacological sciences in advancing regenerative medicine technologies but reports no new experimental findings; the authors advocate for increased pharmacologist involvement to drive innovations.
46 citations
,
September 2014 in “Steroids” This review suggests that brassinosteroids may have similar biological activities in both plants and other organisms, prompting further exploration of steroid regulation mechanisms across different life forms.
42 citations
,
April 2012 in “Seminars in Oncology” This review discusses the skin side effects associated with targeted cancer therapies and reports no new clinical results; it emphasizes the need for empirical management based on expert opinion.
40 citations
,
February 2020 in “Experimental and Therapeutic Medicine” This study found that autologous serum platelet-rich plasma improved skin quality and reduced wrinkles, texture, and pores in healthy females, partly by regulating the expression of MMP-1, tyrosinase, fibrillin, and tropoelastin.
39 citations
,
April 2024 in “Frontiers in Endocrinology” This study reviews the causes, mechanisms, and treatments for thin endometrium, highlighting multiple contributing factors such as hormonal influences, long-term oral contraceptive use, and uterine inflammation, while noting unclear mechanisms in promising therapeutic strategies like pharmacological treatments and regenerative medicine approaches.
37 citations
,
May 2018 in “Journal of Cosmetic Dermatology” This review analyzed clinical trial protocols for platelet-rich plasma preparation in hair loss treatment, finding inconsistent and insufficient reporting that complicates comparison and efficacy determination.
34 citations
,
May 2021 in “Journal of Nanobiotechnology” This study found that electrospun short fibrous sponges effectively mimic the 3D extracellular matrix, promoting tissue regeneration, angiogenesis, and wound healing in diabetic rats better than 2D fiber membranes.
33 citations
,
February 2019 in “Journal of Tissue Engineering and Regenerative Medicine” This review discusses the use of platelet-rich plasma for various dermatological conditions and highlights the need for more research to standardize its protocols and understand its biological mechanisms.
30 citations
,
March 2017 in “ACS biomaterials science & engineering” This review discusses the structure and regenerative potential of hair follicles, highlighting their role in wound healing, stem cell populations, and keratin-based biomaterials, but it reports no new clinical results.
29 citations
,
September 2020 in “International Journal of Molecular Sciences” This review outlines the current state of freeze-dried platelet-rich plasma (FD-PRP) research, emphasizing its use in wound healing, lumbar fusion, knee conditions, and dentistry, but reports no new clinical findings.
28 citations
,
September 2020 in “Pharmaceutics” This review discusses the potential of three-dimensional printed mesoporous scaffolds for drug delivery applications, particularly for bone cells and tissues, but reports no new clinical results.
28 citations
,
January 2017 in “Critical Reviews in Therapeutic Drug Carrier Systems” This review classifies engineered nanomaterials by composition and application in biomedicine, highlighting diverse uses like regenerative medicine and potential occupational side effects, but reports no new clinical results.
24 citations
,
January 2021 in “Dermatologic Therapy” This review found that platelet-rich plasma therapy improved hair growth and thickness in most studies on alopecia, with the highest improvement seen when combined with Minoxidil.
22 citations
,
October 2019 in “Dermatologic Surgery” This study found that platelet-rich plasma was effective for hair regrowth in women with androgenic alopecia, though less so than minoxidil, but it was associated with improved quality of life responses.
21 citations
,
March 2018 in “Experimental Dermatology” This practical guide introduces methods to study human dermal white adipose tissue but does not report new clinical results, emphasizing available techniques and staining protocols.
20 citations
,
July 2009 in “Journal of Pediatric and Adolescent Gynecology” This article reviews various hair abnormalities in adolescents and young adults and emphasizes the importance of timely diagnosis and education for optimal patient outcomes, but it reports no new clinical results.
19 citations
,
August 2019 in “Seminars in Plastic Surgery” This review explains the biology and preparation of platelet-rich plasma and discusses its clinical applications in plastic surgery, but reports no new findings.
18 citations
,
February 2006 in “Brain & development” This case study reports successful treatment of a 19-year-old with Satoyoshi syndrome using a combination of carbamazepine, methotrexate, prednisolone, and sex-steroids, improving muscle spasms, alopecia, and quality of life.
17 citations
,
January 2010 in “PubMed” This review explores factors affecting graft growth and survival in hair restoration, emphasizing the importance of fundamental care practices while considering advanced storage solutions and additives, but reports no new findings.
15 citations
,
July 1997 in “Clinics in Dermatology” Traditional Chinese medications can cause skin reactions, and better testing and reporting are needed to identify allergens.
14 citations
,
November 2020 in “International Journal of Molecular Sciences” This review article summarizes the potential role of advanced medical therapies—using genes, cells, and/or tissue engineering—in treating various types of alopecia, by examining clinical research, basic studies, and ongoing trials.
14 citations
,
June 2019 in “Dermatologic therapy” This study found that autologous platelet-rich plasma injections showed no significant effect on hair regrowth in patients with alopecia areata totalis.
13 citations
,
January 2020 in “Experimental Dermatology” This pilot clinical trial suggests that platelet-rich plasma (PRP) treatment may increase hair density in patients with androgenetic alopecia, though outcomes varied between patients.
13 citations
,
June 2016 in “Journal of neurological surgery” This study suggests that leukocyte-platelet-rich fibrin membranes may aid postoperative healing in endoscopic skull base surgery, with some patients showing reduced crusting and low rates of cerebrospinal fluid leaks.
12 citations
,
September 2021 in “The International Journal of Developmental Biology” This review updates on the development of liposomal carriers for delivering growth factors to improve tissue regeneration and highlights recent efforts to enhance their stability and retention in tissues.
12 citations
,
December 2020 in “Frontiers in Cell and Developmental Biology” This review covers the variability in methods for preparing platelet-rich plasma and reports no new clinical results, suggesting that this variability may contribute to inconsistent efficacy in clinical trials.
12 citations
,
March 2018 in “Bioengineering” This review discusses the use of non-transfusional hemocomponents in surgical procedures for tissue regeneration and reports no new empirical findings.
12 citations
,
October 2017 in “Journal of Cosmetic Dermatology” This study found that plasma rich in growth factors (PRGF) as an adjuvant to follicular unit extraction (FUE) surgery may enhance hair graft performance and reduce post-surgical inflammation and pain in hair loss patients.