research Pharmacokinetic-Pharmacodynamic Modeling Approach for Dose Prediction of the Optimal Long-Acting Injectable Formulation of Finasteride
Optimal long-acting finasteride injection dose found: 16.8 mg, effective for one month.
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research Evaluation of Biophysical Skin Parameters and Hair Changes in Patients with Acne Vulgaris Treated with Isotretinoin, and the Effect of Biotin Use on These Parameters
Biotin supplementation during isotretinoin treatment for acne may help maintain skin hydration and improve hair growth.
research Doping-Control Analysis of the 5α-Reductase Inhibitor Finasteride: Determination of Its Influence on Urinary Steroid Profiles and Detection of Its Major Urinary Metabolite
Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.
research 17-Hydroxyprogesterone Responses to Gonadotropin-Releasing Hormone Reveal Distinct Phenotypes of Functional Ovarian Hyperandrogenism and Polycystic Ovary Syndrome
The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.
research Allergic Contact Dermatitis from Dyes in Wigs Following Diphenylcyclopropenone Treatment
Avoiding dyed wigs and clothing improved severe allergic reactions in a woman treated with diphencyprone.
research Methotrexate for Maintenance of Remission in Ulcerative Colitis
Methotrexate is not proven to maintain remission in ulcerative colitis.
research Chemical Compatibility and Safety of Imidacloprid/Flumethrin Collar (Seresto) Concomitantly Used with Imidacloprid/Moxidectin (Advocate, Advantage Multi) and Emodepside/Praziquantel (Profender) Spot-on Formulations
Seresto® collar is safe to use with Advocate® and Profender® on dogs and cats.
research Botanical Treatment for Polycystic Ovary Syndrome
Some plant-based treatments may help with ovary function, insulin resistance, and excess male hormones in PCOS, but more research is needed to confirm their safety and effectiveness.
research Treatment of Hyperandrogenism in Women
Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.
research Development and Validation of Spectrophotometric Method for Determination of Finasteride in Pharmaceutical Formulation Using 1,2-Naphthoquine-4-Sulfonate
New method accurately measures finasteride in medicine using NQS.
research Finasteride
Finasteride treats enlarged prostate, improves urinary flow, but may cause sexual side effects.
research The Challenges with Managing Polycystic Ovary Syndrome: A Qualitative Study of Women’s and Clinicians’ Experiences
Managing PCOS is hard because it varies a lot, treatments are limited, and there's a lot of false information online.
research Gender-Affirming Hormone Therapy for Transgender Females
Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.
research Tissue Engineering of the Reproductive System
Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.
research A Model for the Turnover of Dihydrotestosterone in the Presence of the Irreversible 5α-Reductase Inhibitors GI198745 and Finasteride
Both drugs lower DHT levels, with GI198745 being more effective.
research Office Dermatology
Most skin conditions can be managed with general medical knowledge.
research The Pharmacologic Treatment of Muscle Pain
The document concludes that more research is needed to understand how to treat muscle pain with drugs.
research Sexual Dysfunction in Men Taking Systemic Dermatologic Medication: A Systematic Review
Some men taking finasteride for hair loss may experience sexual problems like erectile dysfunction and decreased sex drive, which can persist even after stopping the medication.
research Hair Growth Effect of Traditional Chinese Medicine BeauTop on Androgenetic Alopecia Patients: A Randomized Double-Blind Placebo-Controlled Clinical Trial
BeauTop improves hair growth in androgenetic alopecia patients.
research Bioequivalence Study of Two Different Coated Tablet Formulations of Finasteride in Healthy Volunteers
Two finasteride tablet types are equally effective and can be swapped.
research Congenital Adrenal Hyperplasia
Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.
research Principles of Therapy of Skin Diseases
Use the least toxic, most specific treatments for skin diseases, considering side effects and individual patient needs.
research Therapeutic Management of Generalized Canine Demodicosis With Secondary Bacterial and Yeast Infections: A Case Report
The dog fully recovered one month after treatment.
research Advances in Male Hormone Substitution Therapy
New treatments for low male hormones improved sexual function and mood but had unclear risks, especially for older men.
research Persistent Sexual and Nonsexual Adverse Effects of Finasteride in Younger Men
Finasteride can cause sexual problems and depression in young men.
research Healthcare Innovation and Patent Law’s Pharmaceutical Privilege: Is There a Pharmaceutical Privilege? And If So, Should We Remove It?
The document suggests reevaluating the patent system to ensure public benefits from pharmaceutical privileges and to encourage more significant innovations.
research Lifestyle Drugs: Ethical and Practical Issues
The article concludes that a balance is needed between individual healthcare needs and societal resources when it comes to lifestyle drugs, with a call for compassionate policy application.
research South Asian Epidemic of Antifungal Therapeutic Failures: Congress Proceedings and Take-home Messages. First International Congress of SAARCUM: South Asian Alliance Against Recalcitrant Cutaneous Mycosis. 17 November 2018, Medanta – The Medicity, Gurugram, India
The congress concluded that misuse of antifungal drugs in South Asia has led to widespread treatment failure, and new approaches and regional cooperation are needed.
research Polymeric Nanoparticles-Based Topical Delivery Systems for the Treatment of Dermatological Diseases
Polymeric nanoparticles show promise for treating skin diseases.
research Main Plenary Sessions: Summaries of Papers
The document concludes that accurate diagnosis and treatment are crucial in dermatology, and it presents various findings on skin conditions and treatments.