research Early Embryonic Exposure of Freshwater Gastropods to Pharmaceutical 5-Alpha-Reductase Inhibitors Results in a Surprising Open-Coiled 'Banana-Shaped' Shell
Certain drugs change freshwater snail shells to a "banana" shape.
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research Latanoprostene Bunod Ophthalmic Solution 0.024% in the Treatment of Open-Angle Glaucoma: Design, Development, and Place in Therapy
Latanoprostene bunod effectively lowers eye pressure and is better tolerated than other glaucoma medications.
research Treatment of Chronic Alopecia Areata With Tildrakizumab: An Open-Label Pilot Study
Tildrakizumab showed limited effectiveness in treating chronic alopecia areata in a small group of patients.
research An Open-Label Pilot Clinical Trial of the JAK Inhibitor Tofacitinib for Alopecia Areata
Tofacitinib, a JAK inhibitor, improved hair regrowth in most patients with severe alopecia areata and had minimal side effects.
research An Open Label Clinical Trial of the JAK Inhibitor Tofacitinib for Alopecia Areata
Tofacitinib helped over half of the patients with severe hair loss regrow at least 50% of their hair.
research Molecular Correlation With Clinical Outcomes in an Open Label Clinical Trial of Oral Tofacitinib in Patients With Alopecia Areata
Tofacitinib helped most patients with alopecia areata regrow hair and changes in immune cells were linked to the treatment's effectiveness.
research Efficacy and Safety of a New Topical Hair Loss Lotion Containing Oleanolic Acid, Apigenin, Biotinyl Tripeptide-1, Diaminopyrimidine Oxide, Adenosine, Biotin, and Ginkgo Biloba in Patients with Androgenetic Alopecia and Telogen Effluvium: A Six-Month Open-Label Prospective Clinical Study
Hair loss lotion with specific ingredients effectively improves hair growth and thickness safely.
research An Open Label Trial Evaluating the Use of Microneedling in Hair Loss
Microneedling mildly regrows hair in androgenetic alopecia but not in other types.
research Commercial and Open-Source Systems
Commercial and open-source light sheet microscopy systems have advanced through engineer-scientist collaborations, improving imaging quality.
research Efficacy and Safety of Proxalutamide in Severe or Critically Ill COVID-19 Patients: Study Protocol for an Exploratory Trial
The trial will test if proxalutamide is safe and effective in reducing death in severe COVID-19 patients.
research Ageratum Conyzoides L. Extract Inhibits 5α-Reductase Gene Expression and Prostaglandin D2 Release in Human Hair Dermal Papilla Cells and Improves Symptoms of Hair Loss in Healthy Males and Females in an Open Label Pilot Study
Ageratum conyzoides L. extract may effectively and safely treat hair loss.
research A Prospective Open Labelled Phase-II Non-Randomized Clinical Trial on Karunjchirakam Chooranam for Poly Cystic Ovarian Syndrome
Karunjchirakam Chooranam significantly improved symptoms in most PCOS cases.
research Quality of Life After Endovascular Repair Versus Open Surgery for Abdominal Aortic Aneurysms
Endovascular repair and open surgery for abdominal aortic aneurysms both result in a temporary decline in physical health, with no significant mental health difference, and a return to near normal health in 90 days.
research A Randomized Open Label Comparative Study of Hydroxychloroquine with Betamethasone Oral Minipulse in the Management of Patients with Alopecia Areata
Betamethasone is more effective long-term for alopecia areata than hydroxychloroquine.
research Cessation of Hairline Recession Following Open Forehead Rejuvenation
Surgical deactivation can significantly reduce or eliminate migraine symptoms.
research Finasteride Inhibited Brain Dopaminergic System and Open-Field Behaviors in Adolescent Male Rats
Finasteride affects young male rats' brain function and behavior negatively.
research Real-World, Open-Label Study of the Efficacy and Safety of a Novel Serum in Androgenetic Alopecia
REVIVV® serum improves hair growth and reduces shedding in androgenetic alopecia.
research Comparison of the Effects of Aloe Vera Gel and Coconut Oil on the Healing of Open Wounds in Rats
Aloe vera gel helps heal open wounds better than coconut oil.
research Janus Kinase Inhibitors for the Treatment of Severe Alopecia Areata: An Open-Label Comparative Study
Both ruxolitinib and tofacitinib are effective and safe for treating severe alopecia areata, but relapses are common.
research Feline Acne and Results of Treatment with Mupirocin in an Open Clinical Trial: 25 Cases (1994–1996)
Mupirocin ointment effectively treats feline acne.
research Simvastatin/Ezetimibe Therapy for Recalcitrant Alopecia Areata: An Open Prospective Study of 14 Patients
Simvastatin/ezetimibe may help some patients with severe alopecia areata regrow hair.
research Determination of the Sildenafil Effect on Alopecia Areata in Childhood: An Open-Pilot Comparison Study
Topical 1% sildenafil is not recommended for treating alopecia areata in children.
research Use of an Alternating Inflatable Head Pad in Patients Undergoing Open Heart Surgery
An alternating inflatable head pad reduced pressure ulcers and hair loss in heart surgery patients.
research Pharmacokinetic Interaction of Finasteride With Tamsulosin Hydrochloride: An Open-Label, Randomized, Three-Period Crossover Study in Healthy Chinese Male Volunteers
Finasteride and tamsulosin hydrochloride can be safely taken together without significant interaction.
research A Phase I, Open-Label, Sequential, Single-Dose Clinical Trial to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of IVL3001, a Finasteride-Based Novel Long-Acting Injection for Androgenetic Alopecia
IVL3001 is safe, effective, and better than oral finasteride for treating hair loss.
research Supplementary Material for: Turpentine Ointment for the Treatment of Folliculitis – An Open, Prospective, Randomized, Placebo- and Comparator-Controlled Multicenter Trial
Turpentine ointment is effective and safe for treating folliculitis.
research Supplementary Material for: Turpentine Ointment for the Treatment of Folliculitis – An Open, Prospective, Randomized, Placebo- and Comparator-Controlled Multicenter Trial
Turpentine ointment is an effective and safe treatment for folliculitis.
research Efficacy and Safety of a Botanical Shampoo Containing Morus Alba Root Extract in Republic of Korea: A Single-Center, Open-Label, Pilot Study in Mild to Moderate Non-Scarring Alopecia of the Scalp
The botanical shampoo with Morus alba root extract is safe and effective for treating hair loss.
research Comparative Efficacy of Topical Minoxidil Alone Against Combination of Topical Minoxidil and Platelet Rich Plasma in Women with Female Pattern Hair Loss - A Pilot, Open Randomized Trial
Minoxidil alone is as effective as combining it with PRP for treating female pattern hair loss.
research A Randomized, Open Label Comparative Study of Hydroxychloroquine with Betamethasone Oral Mini Pulse in the Management of Patients with Alopecia Areata
Hydroxychloroquine is less effective than betamethasone oral mini pulse therapy for treating alopecia areata.