Comparative Efficacy of Topical Minoxidil Alone Against Combination of Topical Minoxidil and Platelet Rich Plasma in Women with Female Pattern Hair Loss - A Pilot, Open Randomized Trial

This pilot, open randomized trial compared the efficacy and safety of topical minoxidil 2% alone versus a combination of topical minoxidil 2% and platelet-rich plasma (PRP) in 26 women with female pattern hair loss (FPHL). Both groups showed significant increases in hair density (34.92 ± 8.39 hairs/cm² for the combination group and 31.21 ± 8.30 hairs/cm² for the minoxidil-only group) and significant reductions in hair pull test results. Patient satisfaction scores were similar, with 16.7% in the combination group and 28.6% in the minoxidil-only group reporting high satisfaction. No major side effects were observed. The study concluded that while the combination therapy is effective, it is not superior to minoxidil alone, though PRP may be beneficial for patients with compliance issues related to minoxidil.