May 2026 in “JAAD International” This article notes the lack of US prevalence data for primary lymphocytic cicatricial alopecias due to the recent introduction of subtype-specific ICD-10 codes and highlights the importance of early diagnosis for hair preservation.
26 citations
,
January 1992 in “Carcinogenesis” This study suggests that chronic treatment with TPA in mouse skin selectively expands a keratinocyte subpopulation hyperinducible for ODC, which may be a key target for neoplastic transformation.
37 citations
,
February 2007 in “Clinical Obstetrics and Gynecology” This article examines current pharmacologic treatments for PCOS focusing on symptom-specific approaches, particularly the metabolic effects of therapies, but reports no new clinical findings.
15 citations
,
September 2015 in “Journal der Deutschen Dermatologischen Gesellschaft” This review discusses OCD spectrum disorders with dermatological symptoms, emphasizing their clinical features, neurobiology, and treatment options, while noting the need for more controlled studies.
11 citations
,
March 2021 in “Reproductive Biology and Endocrinology” This study found that bloating is the most frequently reported symptom and a main predictor of polycystic ovary syndrome among women using the Flo app across five countries.
36 citations
,
May 2021 in “Nutrients” This review summarizes current knowledge on the efficacy of natural molecule supplementation, such as inositols and omega-3 fatty acids, in managing PCOS symptoms but reports no new clinical results.
3 citations
,
September 2025 in “Frontiers in Cardiovascular Medicine” This study reports that women with polycystic ovary syndrome, especially those with a hyperandrogenic pattern, are at a higher risk for cardiovascular disease compared to other PCOS patients, likely due to related metabolic comorbidities.
2 citations
,
December 2021 in “Cureus” This study found that cutaneous manifestations are prevalent in PCOS patients, with 68% experiencing symptoms like hirsutism and acne, highlighting the need for better awareness across medical specialties.
This study presents the G4 transgenic mouse model, which suggests a direct link between polycystic ovary syndrome and the Gm10800 gene, offering a valuable tool for understanding the disease and testing treatments.
August 2020 in “Journal of Womens Health, Issues and Care” This review summarizes existing medications for Polycystic Ovary Syndrome, highlighting herbal treatments, but does not report new clinical results.
This study found that an extract treatment showed similar efficacy and tolerability to calcipotriol/betamethasone ointment in reducing psoriasis severity and symptoms over 28 days in patients with mild-to-moderate plaque psoriasis.
July 2011 in “Journal of Nursing UFPE on line” This study found that 13% of women who underwent ultrasound imaging showed suggestive signs of polycystic ovaries, but ultrasound findings alone are insufficient to diagnose polycystic ovary syndrome.
1 citations
,
October 2025 in “Human Reproduction” This study found that in women with PCOS, anxiety was linked to factors like alopecia and obesity, while depression was related to unemployment and alopecia, and body appreciation was lower with conditions like hirsutism and acne.
19 citations
,
May 1984 in “Digestive diseases and sciences” A young woman's Cronkhite-Canada syndrome improved on its own after she gave birth.
January 2026 in “International journal of research and scientific innovation” In this review, the authors emphasize that dietary changes, nutraceuticals, and herbal remedies like curcumin, berberine, and cinnamon can potentially improve metabolic and reproductive health, making these interventions promising for managing PCOS alongside traditional pharmaceutical treatments.
131 citations
,
August 2004 in “Best Practice & Research in Clinical Obstetrics & Gynaecology” This article reviews the complex pathophysiology of polycystic ovary syndrome, highlighting how genetic, hormonal, and environmental factors contribute to its diverse symptoms, and reports no new results.
81 citations
,
May 2019 in “Frontiers in Endocrinology” This study found that administering melatonin for 12 weeks to women with PCOS significantly reduced hirsutism, testosterone, and inflammation markers, while enhancing antioxidant levels compared to a placebo.
November 2023 in “International Journal of Dermatology” In this study, CCCA patients were found to have higher odds of metabolic, autoimmune, atopic, and psychiatric comorbidities compared to matched controls.
2 citations
,
June 2017 in “Journal of The American Academy of Dermatology” This article discusses the uncertainty regarding distinct skin findings and cardiometabolic profiles among PCOS subtypes and reports no new clinical data.
August 2023 in “JAAD international” This study, conducted at Montefiore Medical Center, reports that central centrifugal cicatricial alopecia predominantly affects middle-aged Black or African American women, often presenting without symptoms, which may delay diagnosis and treatment. The study underscores the need for a specific ICD-10 code for better epidemiological studies.
1 citations
,
October 2023 in “Egyptian Journal of Immunology” This study found that women with PCOS had significantly higher levels of the pro-inflammatory chemokine MIP-1α compared to controls, suggesting an association with low-grade chronic inflammation, though the increase in MIP-1β levels did not reach statistical significance.
August 2015 in “Postgraduate obstetrics & gynecology” Women with PCOS often have insulin resistance, abnormal lipid levels, and a higher risk of diabetes and heart disease; lifestyle changes and medication like metformin can help manage these risks.
January 2022 in “IntechOpen eBooks” This review examines lesser-known factors contributing to polycystic ovarian syndrome and reports no new clinical results, emphasizing the need for further research into individualized treatment and prevention strategies.
July 2023 in “Journal of Nursing Science Benha University (Print)” In this study conducted at Benha University Hospital, researchers found that most women with polycystic ovary syndrome had poor knowledge of the condition and over two-thirds experienced a low quality of life, with a significant positive correlation between knowledge level and quality of life scores.
10 citations
,
October 2014 in “Journal of Ovarian Research” This study found a significant association between the IRS-2 gene variant and an increased risk of PCOS, especially in non-obese women in the Chinese population from Taiwan.
January 2009 in “Epsilon: Revista de la Sociedad Andaluza de Educación Matemática "Thales"” This report describes a Cronkhite-Canada syndrome patient with severe sepsis and disseminated intravascular coagulation successfully treated using combined therapies, including recombinant human soluble thrombomodulin.
15 citations
,
January 2019 in “Gynecological Endocrinology” This article discusses the need for a globally standardized protocol for epidemiologic studies of polycystic ovary syndrome to improve study comparability and public health policy.
9 citations
,
March 2022 in “Frontiers in Endocrinology” This study found that PCOS is common among Iranian women, with phenotypes involving hyperandrogenism exhibiting worse lipid profiles and higher rates of metabolic syndrome compared to healthy women.
September 2022 in “PubMed” In this observational study, researchers reported beneficial results in treating an 18-year-old female with PCOS using individualized homeopathy and lifestyle modifications over one year, suggesting this approach as a complementary treatment option.
50 citations
,
November 2020 in “Physiology & behavior” This review found that patients with depression generally have higher hair cortisol concentrations compared to healthy controls, while those with PTSD tend to have lower concentrations.