Natural Molecules in the Management of Polycystic Ovary Syndrome: An Analytical Review

    May 2021 in “ Nutrients
    Matteo Iervolino, Elisa Lepore, Gianpiero Forte, Antonio Simone Laganà, Giovanni Buzzaccarini, Vittorio Unfer
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    TLDR Natural molecules like inositols, resveratrol, vitamins, and omega-3 fatty acids may help manage Polycystic Ovary Syndrome (PCOS), but their effects vary and need more exploration.
    The review discusses the potential benefits of natural molecules in managing Polycystic Ovary Syndrome (PCOS), a disorder affecting up to 25% of women of reproductive age. The molecules include inositols, resveratrol, flavonoids and flavones, vitamin C, vitamin E and vitamin D, and omega-3 fatty acids. The combination of Myo-Ins and D-Chiro-Ins in a 40:1 ratio has been found effective in restoring ovulation and normalizing crucial parameters in overweight and obese PCOS patients. Other molecules like resveratrol, naringenin, vitamins C, E, and D, and omega-3 fatty acids also show potential in managing PCOS, but their effects vary and more studies are needed. Omega-3 fatty acids, in particular, improve symptoms of PCOS in women over 40 years of age, but careful monitoring is necessary due to possible adverse effects.
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