6 citations,
October 2018 in “Endocrinology” Prenatally androgenized ewes can model increased hair diameter in women with PCOS.
4 citations,
November 2012 in “Obstetrics, Gynaecology & Reproductive Medicine” Lifestyle changes and clomiphene are first-line treatments for infertility in women with PCOS, with other options available if these fail.
1 citations,
July 2021 in “Current Issues in Molecular Biology” Father's finasteride use may affect son's fertility and testicular function.
January 2024 in “Theranostics” HDAC6 helps keep ovarian follicles dormant, extending female fertility.
3 citations,
December 2018 in “Biomedical and pharmacology journal/Biomedical & pharmacology journal” Compound 3 protects the heart from damage by activating A1-adenosine receptors.
14 citations,
April 2022 in “Climacteric” Menopause causes dry skin, wrinkles, and hair changes, with hormone therapy helping but not recommended just for these issues.
6 citations,
September 2023 in “International journal of molecular sciences” Oxidative stress worsens PCOS by damaging cells and disrupting metabolism, suggesting antioxidant treatments might help.
May 2020 in “Authorea (Authorea)” Olfactory receptors found outside the nose may offer new treatments for diseases like cancer and help in wound healing and hair growth.
December 2022 in “Journal of Medical Case Reports” A 20-year-old woman was found to have a rare ovarian tumor causing symptoms like acne and a low-pitched voice, which disappeared after the tumor was removed.
7 citations,
May 2015 in “General and Comparative Endocrinology” Finasteride negatively affects fish reproduction and gonadal development.
40 citations,
April 2014 in “Genes & Development” Hormones during pregnancy and lactation keep skin stem cells inactive, preventing hair growth.
88 citations,
May 2012 in “Human Reproduction Update” Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.
2 citations,
January 2017 PCOS is a common hormonal disorder in women that can lead to various health issues and requires comprehensive management.
9 citations,
June 2020 in “Actas Dermo-Sifiliográficas” Spironolactone is effective for acne, hidradenitis suppurativa, female hair loss, and hirsutism but is underused in dermatology.
3 citations,
February 2015 in “Mechanisms of development” Hormones and stretching both needed for nipple area skin growth in mice.
2 citations,
November 2012 in “InTech eBooks” The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.
7 citations,
January 1989 in “Archives of Dermatological Research” The side gland of Suncus murinus is a good model for studying human sebaceous glands.
2 citations,
May 2012 in “Annals of Oncology” Patients with advanced breast cancer and high hormone receptor levels who had surgery for ovarian/pelvic metastases lived longer, especially if they had high estrogen receptor levels.
97 citations,
March 2009 in “Dermato-endocrinology” Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.
1 citations,
February 2014 in “Archiv Der Pharmazie” Carbamates may help treat androgen-dependent conditions by changing how certain lipid enzymes are produced.
March 2023 in “Revista médica Clínica Las Condes” The study suggests a possible increase in androgen receptors in patients with frontal fibrosing alopecia, but more research is needed.
130 citations,
June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).
77 citations,
April 2004 in “Gene expression patterns” The three estrogen receptor genes are highly expressed in zebrafish neuromasts during development.
28 citations,
January 2012 in “Biological & pharmaceutical bulletin” Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.
21 citations,
May 2015 in “The Journal of Steroid Biochemistry and Molecular Biology” Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.
73 citations,
June 2001 in “Endocrinology” Prolactin affects when mice shed and grow hair.
20 citations,
July 2006 in “Veterinary dermatology” Melatonin helped some Pomeranian dogs regrow hair, but it wasn't linked to estrogen receptors.
14 citations,
June 2001 in “Endocrinology” Prolactin affects when mice shed and grow hair.
7 citations,
July 2014 in “Reproductive Biomedicine Online” The length of CAG repeats in the androgen receptor gene is linked to ovarian reserve but does not affect how the ovaries respond to stimulation.
6 citations,
January 2010 in “Neoplasma” Certain gene patterns in breast cancer are linked to how active hormone receptors are and could affect patient survival.