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The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.

Lecithin organogels could be good for applying drugs to the skin because they are stable, safe, and can improve drug absorption.

A gene called APCDD1, which controls hair growth, is found to be faulty in a type of hair loss called hereditary hypotrichosis simplex.

Researchers found 19 genes important for root hair growth in a plant called Arabidopsis.

ATP-dependent chromatin-remodeling complexes are crucial for gene regulation, cell differentiation, and organ development in mammals.

Androgens can help prevent memory problems caused by apoE4.

Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

The peptide GHK-Cu helps heal and remodel tissue, improves skin and hair health, and has potential for treating age-related inflammatory diseases.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Different types of stem cells with unique roles exist in blood, skin, and intestines, and this variety is important for tissue repair.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Men generally have more severe COVID-19 cases and higher death rates than women due to biological differences.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Different PIN proteins affect plant root hair growth by changing how auxin is transported.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Potassium channel openers could help treat cardiovascular diseases and asthma but require better targeting to specific tissues for effective use.

The AUTS2 gene is linked to neurological disorders and may affect human brain development and cognition.

MIM is crucial for hair follicle formation and regeneration by controlling cilia formation and hedgehog signaling through its interaction with Cortactin and Src.

Hair grows faster in the morning and is more vulnerable to damage from radiation due to the internal clock in hair follicle cells.

Scientists turned rat thymus cells into stem cells that can help repair skin and hair.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

Too much Smad7 can cause serious changes in skin tissues, including problems with hair growth, thymus shrinkage, and eye development issues.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.