research Hormonal Regulation in Male Androgenetic Alopecia: Sex Hormones and Beyond - Evidence from Recent Genetic Studies
Hormones and genes affect hair growth and male baldness.
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research The Antiandrogen Enzalutamide Downregulates TMPRSS2 and Reduces Cellular Entry of SARS-CoV-2 in Human Lung Cells
The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.
research Safety of Antiandrogens for the Treatment of Female Androgenetic Alopecia with Respect to Gynecologic Malignancies
Spironolactone is safe for treating female hair loss, but the safety of other drugs is uncertain.
research Androgen Receptor (AR) Gene (CAG)n and (GGN)n Length Polymorphisms and Symptoms in Young Males With Long-Lasting Adverse Effects After Finasteride Use Against Androgenic Alopecia
Finasteride side effects in young men may be linked to specific gene variations.
research Alopecia: The Search for Novel Agents Continues
Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.
research Spinal and Bulbar Muscular Atrophy: Pathogenesis and Clinical Management
Kennedy's disease leads to muscle weakness without a cure, but exercise and managing symptoms may help patients live a normal lifespan.
research Early Onset and Novel Features in a Spinal and Bulbar Muscular Atrophy Patient with a 68 CAG Repeat
A patient with a larger than usual genetic mutation had a broader range of symptoms for a muscle disease.
research Revising the Role of the Androgen Receptor in Breast Cancer
The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.
research Molecular Interactions of New Pregnenedione Derivatives
The new progesterone derivatives effectively inhibit 5α-reductase and bind to the androgen receptor.
research Clinical Biochemistry of Dihydrotestosterone
Understanding how DHT works is important for diagnosing and treating hormone-related disorders.
research Differential Expression of CXCL12 in Human and Mouse Hair: Androgens Induce CXCL12 in Human Dermal Papilla and Dermal Sheath Cup
Targeting CXCL12 may help treat hair loss caused by androgens.
research Platelet Factor 4 Inhibits Human Hair Follicle Growth and Promotes Androgen Receptor Expression in Human Dermal Papilla Cells
Platelet factor 4 slows down hair growth and could make hair loss treatments more effective if removed.
research SARS-CoV-2 and Androgenic Alopecia: Exploring Links
Possible link between COVID-19 and hair loss; more research needed.
research Hormonal Therapy in Female Pattern Hair Loss
Hormonal therapies help treat female hair loss, but results are slow and vary.
research Spironolactone and XPB: An Old Drug with a New Molecular Target
Spironolactone, a heart and liver drug, has new uses including cancer treatment, viral infection prevention, and skin condition improvement.
research Cross-Species Sensitivity to a Novel Androgen Receptor Agonist of Potential Environmental Concern, Spironolactone
Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.
research Pharmacological Options for Treatment of Hyperandrogenic Disorders
Different drugs can treat high male hormone levels in women, but they have various effects and some may harm a fetus.
research Idiopathic Hirsutism: Androgen Role and Treatment Options
The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.
research Androgens and Hair Growth
Androgens can both increase and decrease hair growth in different parts of the body.
research Hair Thickness Growth Effect of Adenosine Complex in Male and Female Patterned Hair Loss via Inhibition of Androgen Receptor Signaling
Adenosine complex helps increase hair thickness and density in hair loss.
research Molecular Docking Studies and ADME-Tox Prediction of Phytocompounds from Merremia Peltata as a Potential Anti-Alopecia Treatment
The compound 16 from the Merremia peltata plant could potentially be a good treatment for hair loss (alopecia) due to its strong activity and favorable skin absorption.
research Androgen Effects in Mammals
Testosterone is crucial for development, growth, and various body functions in mammals.
research Boosting Hair Follicle Regeneration
A protein called FGF9 helps regenerate hair follicles in mice after skin damage, and increasing FGF9 could potentially help human hair growth.
research Effects of Flutamide, a Pure Antiandrogen, on Endocrine Parameters in the Adult Female Rat
Flutamide, an antiandrogen, has minimal impact on female rat endocrine systems and does not significantly change their reproductive cycles.
research Effects of Allium Hookeri Extracts on Hair-Inductive and Anti-Oxidative Properties in Human Dermal Papilla Cells
Allium hookeri extract may help promote hair growth and protect cells from damage.
research Treatment of Hirsutism With Spironolactone
Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.
research Recent Approaches of Antibody Therapeutics in Androgenetic Alopecia
Antibody treatments show promise for hair loss but need more research.
research Estrogens and Aging Skin
Estrogen therapy can reduce skin aging but has cancer risks.
research Estrogen Functions in Skin and Skin Appendages
Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.
research Multiple Readout Assay for Hormonal (Androgenic and Antiandrogenic) and Cytotoxic Activity of Plant and Fungal Extracts Based on Differential Prostate Cancer Cell Line Behavior
The study created a test that found hormonal and toxic effects in plant and fungal extracts using prostate cancer cells.