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Hair follicles can be used to quickly assess drug effects in cancer treatment.

Melanocytes are important for skin and hair color and protect the skin from UV damage.

Unconventional lymphocytes are important for quick immune responses and healing of skin and mucosal barriers.

Abnormal Hedgehog signaling in blood cancers may help tumors grow and resist chemotherapy, suggesting potential for targeted treatments.

Androgens may influence T cells, contributing to higher autoimmune liver disease risk in women.

Melanoma's complexity requires personalized treatments due to key genetic mutations and tumor-initiating cells.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Cell polarity signaling controls tissue mechanics and cell fate, with complex interactions and varying pathways across species.

The conclusion is that skin and hair patterns are formed by a mix of cell activities, molecular signals, and environmental factors.

Gene therapy, especially using atoh1, shows promise for creating functional sensory hair cells in the inner ear, but dosing and side effects need to be managed for clinical application.

Removing centrosomes from skin cells leads to thinner skin and stops hair growth, but does not greatly affect skin cell differentiation.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Skin tumor regression is helped by retinoic acid signaling blocking Wnt signaling.

Faulty Notch signalling may cause hair follicle changes and inflammation in hidradenitis suppurativa.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

Jagged-1 in skin Tregs is crucial for timely wound healing by recruiting specific immune cells.

Regulatory T-cells are important for healing and regenerating tissues in various organs by controlling immune responses and aiding stem cells.

Special immune cells called Treg cells are important for maintaining and regenerating hair by activating a specific growth signal in hair stem cells.

JAGGED1 could help regenerate tissues for bone loss and heart damage if delivered correctly.

FoxN1 gene is essential for proper thymus structure and preventing hair loss.

Hair growth and development are controlled by specific signaling pathways.

Multi-omics techniques help understand the molecular causes of androgenetic alopecia.

Innate lymphoid cells help control skin bacteria by regulating sebaceous glands.

Adam10 enzyme is crucial for healthy skin and proper Notch signaling.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

Hair follicle regeneration may slow tumor growth.

Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.

Researchers created rat liver stem cells that could help repair liver failure in rats and may be useful for studying human liver diseases.

Removing a methyl group from the ITGAV gene speeds up bone formation in a specific type of bone disease model.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.