research Tissue Regenerative Delays and Synthetic Lethality in Adult Mice After Combined Deletion of ATR and TRP53
Removing both Atr and Trp53 genes in adult mice causes severe tissue damage and death due to DNA damage.
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research Melanogenesis Is Coupled to Murine Anagen: Toward New Concepts for the Role of Melanocytes and the Regulation of Melanogenesis in Hair Growth
Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.
research An ERK-Dependent Molecular Switch Antagonizes Fibrosis and Promotes Regeneration in Spiny Mice
High levels of ERK activity are key for tissue regeneration in spiny mice, and activating ERK can potentially redirect scar-forming healing towards regenerative healing in mammals.
research Nongenomic Effects of 1α,25-Dihydroxyvitamin D3 on Cartilage Formation Deduced from Comparisons Between Cyp27b1 and Vdr Knockout Mice
1α,25-dihydroxyvitamin D3 directly affects cartilage growth and development.
research Metabolomic Analysis of SMP30/GNL Knockout Mice Treated with Fermented Vegetable and Fruit Extract (OM-X)
OM-X® helped prevent negative effects of Vitamin C deficiency in mice, suggesting it could protect organs and regulate metabolism.
research Long-Term Treatment with Finasteride Induces Apoptosis and Pathological Changes in Female Mice
Finasteride causes harmful organ changes in female mice.
research Analysis of Androgen Receptor Expression and Activity in the Mouse Brain
Androgen receptors in the mouse brain may explain cognitive and mood changes in prostate cancer treatment.
research UVB-Induced Depletion of Donor-Derived Dendritic Cells Prevents Allograft Rejection of Immune-Privileged Hair Follicles in Humanized Mice
UV light helped human hair transplants survive in mice without broad immunosuppression.
research Irradiation-Induced Hair Graying in Mice: An Experimental Model to Evaluate the Effectiveness of Interventions Targeting Oxidative Stress, DNA Damage Prevention, and Cellular Senescence
Using radiation to make mice's hair turn gray helps study and find ways to prevent or reverse hair graying.
research CD133-Positive Dermal Papilla-Derived Wnt Ligands Regulate Postnatal Hair Growth
Wnt proteins from certain skin cells are crucial for normal hair growth and renewal.
research Finasteride Inhibits the Disease-Modifying Activity of Progesterone in the Hippocampus Kindling Model of Epileptogenesis
Finasteride worsens seizures in epilepsy rats and speeds up epileptogenesis in mice.
research Deletion of Hypoxia-Inducible Factor Prolyl 4-Hydroxylase 2 in FoxD1-Lineage Mesenchymal Cells Leads to Congenital Truncal Alopecia
Removing HIF-P4H-2 from certain skin cells in mice causes hair loss on the body but not the head.
research Motoneuron-Specific PTEN Deletion in Mice Induces Neuronal Hypertrophy and Regeneration After Facial Nerve Injury
Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.
research In Vivo Response of GsdmA3Dfl/+ Mice to Topically Applied Fish Oil – Effects on Cellular Markers and Macrophages
Fish oil increased cell growth and macrophages in the skin but didn't affect COX-2 expression.
research Cornu Cervi Pantotrichum Pharmacopuncture Solution Facilitates Hair Growth in C57BL/6 Mice
Cornu cervi pantotrichum pharmacopuncture solution helps mice grow hair by increasing hair follicle cell growth and a growth factor important for hair development.
research Order From Disorder: Self-Organization In Mammalian Hair Patterning
Hair patterns in mice are controlled by both a global system dependent on Fz6 and a local self-organizing system.
research Early Skin Seeding Regulatory T Cells Modulate PPARγ-Dependent Skin Pigmentation
Early regulatory T cells are crucial for normal skin pigmentation.
research Inducible, Reversible Hair Loss in Transgenic Mice
Scientists made a mouse that can be made to lose hair and then grow it back.
research Dihydrotestosterone Inhibits Hair Growth in Mice by Inhibiting Insulin-Like Growth Factor-I Production in Dermal Papillae
Dihydrotestosterone (DHT) stops hair growth in mice by lowering a growth factor important for hair.
research New Intranasal and Injectable Gene Therapy for Healthy Life Extension
Gene therapy in mice increased lifespan and improved health without causing cancer.
research Activation of Polyamine Catabolism Profoundly Alters Tissue Polyamine Pools and Affects Hair Growth and Female Fertility in Transgenic Mice Overexpressing Spermidine/Spermine N1-Acetyltransferase
Overexpressing a specific enzyme in mice causes hair loss and female infertility.
research Hair Growth-Promoting Effects of Lavender Oil in C57BL/6 Mice
Lavender oil significantly promotes hair growth in mice.
research Increased Vibrissa Growth in Transgenic Mice Expressing Insulin-Like Growth Factor 1
IGF-1 increases whisker growth in transgenic mice.
research Dihydrotestosterone-Induced Hair Regrowth Inhibition by Activating Androgen Receptor in C57BL6 Mice Simulates Androgenetic Alopecia
DHT stops hair regrowth in mice, similar to human hair loss.
research Alteration of Ethanol Drinking in Mice via Modulation of the GABAA Receptor with Ganaxolone, Finasteride, and Gaboxadol
Three drugs change mice's alcohol drinking patterns by affecting GABAA receptors.
research Integrated Transcriptomics and Metabolomics Analyses of Stress-Induced Murine Hair Follicle Growth Inhibition
Chronic stress in mice changes skin metabolism and gene expression, leading to hair loss.
research Genetic Ablation of Myelin Protein Zero-Like 3 in Mice Increases Energy Expenditure, Improves Glycemic Control, and Reduces Hepatic Lipid Synthesis
Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.
research Cultured Follicles Offer Hope for Beating Baldness
Growing hair follicles from cultured cells could potentially treat baldness, but more research is needed.
research Hair Regrowth Through Wound Healing Process After Ablative Fractional Laser Treatment in a Murine Model
Laser treatment helped regrow hair in mice by activating a key growth pathway.
research On Photo-Stability of Oxybenzone
Estrogen receptors may not affect mouse hair growth as previously thought, and oxybenzone in sunscreen is stable in sunlight.