September 2023 in “Diagnostics” In this study, researchers found a significant relationship between mid-luteal progesterone levels and 25-hydroxy vitamin D levels in infertile patients, suggesting that about 20 ng/mL of vitamin D may be necessary to trigger ovulation or support progesterone secretion.
149 citations
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January 2011 in “Nature reviews. Urology” Hormonal interactions, especially involving DHT and estrogen, play a key role in BPH development and treatment.
38 citations
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December 2020 in “Cancers” This review discusses current clinical trials targeting Wnt signaling in gastrointestinal cancers and reports no new results; the authors highlight challenges and consider alternative strategies for cancer treatment.
26 citations
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January 2016 in “Indian journal of endocrinology and metabolism” In this randomized trial, metformin and pioglitazone both improved certain clinical and metabolic indices in women with PCOS, with pioglitazone showing potential as an alternate treatment for those intolerant to metformin.
3 citations
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December 2016 in “PubMed” This study found that PCOS patients with menstrual disorders exhibited hormonal changes and higher fasting glucose levels, despite no significant differences in insulin resistance markers.
1 citations
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December 2021 in “Animals” This study concluded that thyroid atrophy, alopecia, and hyperkeratosis in sheep are associated with deficiencies in selenium and zinc in serum and liver.
July 2025 in “AACE Endocrinology and Diabetes” Ovarian hyperthecosis caused high testosterone and virilization symptoms in a 60-year-old woman, which improved after surgery.
April 2025 in “The American journal of patient health info.” This source highlights that women with PCOS often face hormonal imbalances leading to symptoms like irregular menstrual cycles and increased risks of conditions such as infertility and type 2 diabetes, while lifestyle changes remain crucial for managing PCOS.
January 2025 in “i-manager s Journal on Life Sciences” This review discusses PCOD's pathophysiology, clinical features, and management strategies but reports no new clinical findings, emphasizing the need for early diagnosis and multidisciplinary management.
October 2024 in “Journal of the Endocrine Society” In this case report, a rare association between Cushing's syndrome caused by ectopic ACTH from cervical cancer is documented, highlighting the diagnostic challenges, treatment complexity, and high morbidity and mortality, with the patient succumbing to septic shock post-surgery.
October 2024 in “Journal of the Endocrine Society” This case report highlighted a rare instance of Cushing's syndrome caused by ectopic ACTH from cervical cancer, demonstrating diagnostic challenges, treatment complexity, and high risks of morbidity and mortality, with less than 10 cases documented overall.
January 2021 in “Case Reports” This case study reports a rare instance of mucinous cystadenoma causing severe virilization in a postmenopausal woman, highlighting a possible link with rapidly progressive hyperandrogenism.
April 2020 in “Journal of the Endocrine Society” This case report describes a 58-year-old woman whose virilization symptoms were linked to a steroid tumor of the ovary, emphasizing the importance of prompt diagnosis and treatment to improve her quality of life.
January 2015 in “International Journal of Research in Medical Sciences” This case report is the first to associate HAIR-AN syndrome with polycystic ovaries, Hashimoto’s thyroiditis, and several metabolic conditions in a 21-year-old woman, emphasizing early diagnosis and management.
1 citations
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November 2019 in “Archives of breast cancer” This review discusses non-oral hormonal contraceptives and other exogenous steroid hormones, reporting they are generally safe for temporary use in women without breast cancer, but data are limited.
55 citations
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August 2003 in “Ultrasound in Obstetrics and Gynecology” This study suggests that ultrasound and color Doppler analyses may enhance the differential diagnosis of GnRH-dependent precocious puberty in girls with premature breast development or pubic hair growth.
44 citations
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June 2017 in “The EMBO Journal” This study reports that the autotaxin–LPA–LPA3 signaling pathway at the embryo-epithelial boundary plays a critical role in decidualization by up-regulating HB-EGF and COX-2 in the uterine epithelium.
19 citations
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July 2019 in “Journal of Endocrinology” This study found that GTx-024 and Danazol had similar effects to dihydrotestosterone on uterine tissue in mice, while GTx-007 showed minimal impact on the parameters tested.
11 citations
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November 2017 in “Hong Kong Medical Journal” This review discusses the increased cardiometabolic risk associated with polycystic ovary syndrome and highlights the need for tailored management, but it reports no new results.
8 citations
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October 2024 in “Frontiers in Cell and Developmental Biology” This review suggests that telocytes in male reproductive organs help organize tissue structure and paracrine factors, impacting organ development and pathology, but more research is needed on their molecular pathways.
October 2016 in “Journal of the Dermatology Nurses’ Association” This update discusses guidelines for dermatology nurses and nurse practitioners on polycystic ovary syndrome but presents no new research findings; it emphasizes their role in early diagnosis through recognizing skin symptoms.
87 citations
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September 2006 in “Clinical Cancer Research” This article reviews the diverse roles of protein kinase C (PKC) isozymes in cancer biology, highlighting their potential as therapeutic targets, but reports no new experimental results.
63 citations
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November 2012 in “Journal of Cellular Biochemistry” This paper discusses the role of Runx1 in epithelial biology and pathology, highlighting its dual function as a tumor promoter and suppressor in different contexts, and reports no new experimental findings.
40 citations
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March 2014 in “Journal of Family Planning and Reproductive Health Care” This review discusses a strategy using ovarian biology to better understand and manage polycystic ovary syndrome but reports no new research findings.
5 citations
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January 2017 in “Acta Endocrinologica” This case report discusses a postmenopausal woman whose hyperandrogenism and metabolic symptoms improved significantly after the surgical removal of an ovarian Leydig cell tumor, confirmed post-operatively.
4 citations
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May 2022 in “BMC Women's Health” This study found that elevated serum AMH levels can be a strong predictor for diagnosing PCOS among women of reproductive age, when used alongside the other Rotterdam criteria.
3 citations
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June 2017 in “Reproductive biomedicine online” In this study, the SRD5A2 rs523349 polymorphism was significantly associated with an increased risk of miscarriage, particularly during the second trimester.
1 citations
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July 2023 in “Frontiers in Immunology” This review highlights the role of chronic stress, oxidative stress, and immune processes in the development of Hashimoto’s thyroiditis and polycystic ovary syndrome, emphasizing the potential of antioxidants in their treatment based on the existing literature.
August 2023 in “Tzu Chi Medical Journal” This study at a medical center in Eastern Taiwan found that female alopecia has diverse causes, including nutrient deficiencies, autoimmune diseases, psychological stress, thyroid conditions, and COVID-19 vaccination, with iron deficiency affecting 70.3% of cases.
April 2020 in “International journal of reproduction, contraception, obstetrics and gynecology” This case study discussed a postmenopausal female with androgenic alopecia and hirsutism due to a Leydig cell tumor, suggesting the importance of further workup in women with severe hirsutism or androgenic alopecia.