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The diagnosis of polycystic ovary syndrome (PCOS) requires a detailed patient history, ultrasound scanning, hormone level checks, and assessments of ovulation, obesity, and insulin resistance. It's a variable condition that needs individualized management and is a significant risk factor for type 2 diabetes.

Anti-androgens can help manage some PCOS symptoms better than metformin but are not more effective than placebos or birth control pills for other symptoms.

Eflornithine HCl 13.9% cream is safe for skin use with mild, temporary irritation.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

Androgen self-administration might be controlled by membrane receptors, not nuclear ones.

High BMI worsens hair growth in women with PCOS.

Natural volatiles and essential oils have health benefits and can enhance the effects of some medicines, but more research is needed to understand how they work and their possible side effects.

New hair follicle-targeting treatments show promise for hair disorders but need more research on safety and effectiveness.

Keratin treatment reduces astrocyte reactivity and inflammation.

A compound named ZCZ90 can increase muscle spindle firing, potentially helping treat muscle spasms and hypertension.

People with severe hair loss have lower zinc levels in their blood.

Minoxidil, originally a blood pressure medication, is effective in treating hair loss in men and women, with different strengths recommended for each.

L-Cysteine may have health benefits, but its effectiveness is still debated due to limited clinical trial data.

Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.

Heavy ion radiation has a more severe and long-lasting effect on mouse intestinal metabolites than gamma radiation.

3,4,5-tri-O-caffeoylquinic acid promotes hair growth by activating the β-catenin pathway.

Keratin proteins are essential for keeping the cells in the human colon healthy and stable.

Conditioned medium from keratinocytes can improve hair growth potential in cultured dermal papilla cells.

The document says that hirsutism in women usually needs hair removal and hormone treatment to manage symptoms and improve well-being.

Tailored treatments for alopecia areata are recommended based on severity and patient needs.

Topical tacrolimus effectively treated scalp lesions, reversed skin atrophy, and promoted hair growth.

Microneedles can cause side effects like infection and allergic reactions, and precautions like test spots and sunscreen are recommended.

Old neuropharmacological drugs might be effective for treating inflammatory skin diseases.

EtG in hair can help detect alcohol use but may be inaccurate in people with certain health conditions.

A substance from Caulerpa racemosa seaweed may protect against skin damage caused by air pollution by reducing oxidative stress and cell death.

The conclusion is that proper diagnosis and long-term treatment, including medication, hair removal, and lifestyle changes, are important for improving hirsutism, especially in PCOS patients.

Nutritional supplements can help manage hair loss and promote hair growth by strengthening hair roots and countering harmful effects of pollution, smoking, and deficiencies in vitamins and minerals.

A significant number of Nigerian women struggling with infertility have Polycystic Ovary Syndrome, with the exact percentage varying based on the diagnostic criteria used.

Levothyroxine is less effective in men with early-onset male-pattern baldness.

The document concluded that more research is needed to understand how estrogen affects the enzyme involved in hirsutism development.