research Use of Cyproterone Acetate in the Treatment of Acne, Hirsutism, and Virilism
Cyproterone acetate is effective for acne but less so for hirsutism and alopecia, with some side effects and quick menstrual cycle recovery after treatment.
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research WNT Signaling in Disease
The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.
research Tregs: Where We Are and What Comes Next?
The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.
research Methotrexate in Dermatology
Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.
research The Senescence–Stemness Alliance: A Cancer-Hijacked Regeneration Principle
Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.
research Development of Liposomal Systems of Finasteride for Topical Applications: Design, Characterization, and In Vitro Evaluation
Liposomes improve finasteride delivery for hair loss treatment, making it a promising option for topical use.
research Wnt/β-Catenin Signaling Pathway Activates Melanocyte Stem Cells In Vitro and In Vivo
The Wnt/β-catenin pathway can activate melanocyte stem cells and may help regenerate hair follicles.
research Regulation of VDR by ΔNp63α Is Associated with Inhibition of Cell Invasion
ΔNp63α helps control a protein that stops cancer cells from spreading.
research Hypaphorine, an Indole-3-Acetic Acid Antagonist Delivered by the Ectomycorrhizal Fungus Pisolithus Tinctorius, Induces Reorganization of Actin and the Microtubule Cytoskeleton in Eucalyptus Globulus ssp. Bicostata Root Hairs
Hypaphorine from a fungus changes the internal structure of Eucalyptus root hairs, stopping their growth.
research Let Astaxanthin Be Thy Medicine
Astaxanthin is a safe antioxidant that may improve heart, skin, eye health, and physical performance, and help manage chronic diseases.
research Polycystic Ovarian Syndrome: A Comprehensive Review of Symptoms, Diagnosis, and Management
PCOS is a complex disorder managed by treating symptoms and requires a team of specialists.
research Expression and Function of Nuclear Receptor Co-Activator 4: Evidence of a Potential Role Independent of Co-Activator Activity
NcoA4 may have roles beyond helping control gene activity, possibly affecting cell behavior and stability.
research Friends Turned Foes: Angiogenic Growth Factors Beyond Angiogenesis
Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.
research LncRNA-000133 from Secondary Hair Follicle of Cashmere Goat: Identification, Regulatory Network, and Its Effects on Inductive Property of Dermal Papilla Cells
A newly found RNA in Cashmere goats may play a role in hair growth and development.
research Hirsutism II: Treatment
The document concludes that various cosmetic and drug treatments are available for hirsutism, and some new drugs show promise.
research Changes in European Legislation Make It Timely to Introduce a Transparent Market Surveillance System for Cosmetics
Europe needs a clear system to watch over cosmetics for safety and to make sure product claims are true.
research The Use of Cyproterone Acetate/Ethinyl Estradiol in Hyperandrogenic Skin Symptoms: A Review
Cyproterone acetate with ethinyl estradiol is effective for treating skin symptoms related to high androgen levels, like in PCOS.
research Polycystic Ovary Syndrome: A Comprehensive Review
The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.
research Evaluation of the 5α-Reductase Inhibitor Finasteride on Reproduction and Gonadal Development in Medaka, Oryzias Latipes
Finasteride negatively affects fish reproduction and gonadal development.
research PCOS: Perspectives from a Pediatric Endocrinologist and a Pediatric Gynecologist
The document concludes that early and personalized treatment for PCOS in adolescents is crucial to manage symptoms and prevent long-term health issues.
research Biological Profile of Cortexolone 17a-Propionate (CB-03-01), a New Topical and Peripherally Selective Androgen Antagonist
CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.
research Finasteride for Hair Loss: A Review
Finasteride helps hair growth but may cause sexual side effects and depression.
research Evaluation of Efficacy of Intradermal Injection Therapy vs Derma Roller Application for Administration of QR678 Neo Hair Regrowth Formulation for the Treatment of Androgenetic Alopecia—A Prospective Study
Intradermal injections improve hair density and thickness better, while derma roller is more convenient.
research Evaluation of Efficacy, Safety, and Reversibility of Combination Regimen of Cyproterone Acetate and Testosterone Buciclate in Bonnet Monkeys
The right dosage of CPA and TB can work as a safe and reversible male contraceptive in monkeys.
research Lymphatic Vessel: Origin, Heterogeneity, Biological Functions, and Therapeutic Targets
Lymphatic vessels are essential for health and can be targeted to treat various diseases.
research Topical Spironolactone in the Treatment of Ocular Graft-Versus-Host Disease
Topical spironolactone may help treat ocular graft-versus-host disease with minimal side effects.
research Androgenetic Alopecia: Diagnostic and Therapeutic Recommendations of the Polish Dermatological Society
Use trichoscopy to diagnose hair loss; treat with minoxidil, finasteride, or dutasteride; consider platelet-rich plasma and spironolactone.
research Alternative Medicine for Hair Loss
Some natural remedies may help with hair regrowth, but more research is needed to confirm their effectiveness and safety.
research The Relationship Between Keratin 18 and Epithelial-Derived Tumors: As a Diagnostic Marker, Prognostic Marker, and Its Role in Tumorigenesis
Keratin 18 helps diagnose and predict cancer progression and affects cancer growth and spread.
research Current Possible Treatment Approaches of Polycystic Ovary Syndrome (PCOS)
Different treatments for PCOS should be tailored to the individual, including lifestyle changes and various medications.