Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This article discusses melanocyte development from neural crest cells and reports no new experimental results; the authors suggest a broader range of functions for melanocytes than previously recognized.

This review article highlights the potential of mesenchymal stem cells, their exosomes, and non-coding RNAs in repairing aging skin tissues due to their ability to secrete beneficial compounds, suggesting their promising role in photoaging treatment without causing immune rejection or granuloma formation.

This study found that thyrotropin-releasing hormone (TRH) acts as a potent stimulator of hair growth in human scalp hair follicles, promoting elongation and prolonging the anagen phase.

This study found that Wnt signaling, crucial for lung development, may be disrupted in severe asthma, potentially affecting cell proliferation and senescence through complex mechanisms.

This review discusses the current understanding of androgen biosynthesis, mechanisms of action, and their roles in human biology, as well as related congenital and acquired disorders, but it reports no new research findings.

This review summarizes the roles of various cells and signaling pathways in skin wound healing, highlights deviations leading to pathological outcomes like chronic wounds, and evaluates cutting-edge approaches such as biomaterials and precision medicine to improve healing and intervention strategies.

This study found that S1PR1 signaling in mouse aortic endothelial cells varied by location and subtype, influencing inflammatory and lymphangiogenic gene expression through distinct molecular pathways.

This article reviews current knowledge and research gaps on growth hormone in hair follicle biology, highlighting its complex role and suggesting further exploration to reveal nonclassical skin functions.

This review synthesizes knowledge on Prostaglandin E2's role in platelet biology and suggests that targeting PGE2 pathways could lead to personalized antiplatelet therapy without affecting hemostasis, but it presents no new results.

This review summarizes current research on molecular pathways, such as Wnt and Notch, that regulate feather follicle development in yellow-feathered broilers, highlighting their potential impact on poultry carcass quality and suggesting areas for future study.

This review synthesizes both traditional and emerging molecular mechanisms of tissue remodeling across different organs, aiming to establish a theoretical basis for precision interventions in pathological conditions, according to the authors.

Human prostate cells produce more WISP1/CCN4 when there's not enough oxygen.

This review summarizes existing knowledge of how the WNT signaling pathway affects mesenchymal stem cells under various conditions, highlighting challenges and mechanisms for clinical applications.

This study found that combining microneedling with 5% minoxidil improved hair growth in Chinese men with androgenetic alopecia, possibly through activating the Wnt/β-catenin signaling pathway.

In this study, treatment with recombinant DKK2 was shown to significantly stimulate hair progenitor cell growth and enhance hair shaft elongation in ex vivo human hair follicle cultures by activating the Wnt/ẞ-catenin signaling pathway, suggesting a potential role for DKK2 in promoting hair growth.

This study reviewed literature on signaling pathways and concluded that these pathways are crucial pharmacological targets, influencing the mechanisms of drugs used in neurological, cardiovascular, and oncological treatments to correct signal transmission disturbances.

This review discusses the role of the hedgehog signaling pathway in hematological cancers and its potential as a therapeutic target; it reports no new clinical findings.

This review investigates molecular mechanisms behind PCOS pathogenesis and discusses potential therapies, but reports no new clinical results.

In this review, the role of DHT in male-type obesity and metabolic diseases is discussed, with increased levels potentially exacerbating cardiovascular disease risk; the paper reports no new results.

This review discusses how targeting TGF-β with specific inhibitors, including components from Traditional Chinese Medicine, may help reduce liver fibrosis by acting through various signaling pathways.

This review discusses the presence of the StAR protein in 17 non-classical steroidogenic tissues, suggesting that advanced detection methods are needed for a complete understanding of its functions in these tissues.

This study found that spironolactone enhanced the effectiveness of non-DNA-damaging cancer drugs gemcitabine and osimertinib in cancer cell lines and a mouse xenograft model, likely by suppressing the anti-apoptotic protein survivin.

This study found that Punica granatum ethanolic leaf extract may alleviate skin fibrosis in rats by modulating inflammation-related pathways and reducing dermal alterations.

Activating the Eda/Edar pathway improves wound healing by enhancing hair follicle growth.

This chapter reviews signaling pathways related to androgenic alopecia in dermal papilla cells of balding human scalps, integrating published information and analysis of molecular interactions, without reporting new clinical results.

This study found that both ethanol and aqueous extracts of Lepidium sativum seeds improved insulin signaling and reduced obesity-related metabolic changes in high-fat diet-fed rats, suggesting potential as a dietary supplement.

This review discusses the dual role of the Wnt/β-catenin pathway in mammalian tissue injury, highlighting its potential for both promoting regeneration and contributing to fibrosis, but presents no new findings.

This review summarizes recent findings on how Wnt signaling proteins play crucial roles in the cutaneous wound healing process but reports no new clinical results.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

This review discusses molecular signaling pathways and nutritional factors influencing feather growth and regeneration in poultry and offers no new results; the authors suggest these insights may guide strategies for producing superior plumage.