July 2025 in “Journal of Investigative Dermatology” Upadacitinib effectively treats pyoderma gangrenosum.
6 citations
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March 2022 in “PLoS ONE” This study suggests that CGE may enhance hair growth by activating β-catenin signaling pathways in human hair dermal papilla cells and promoting the anagen growth phase in mice.
2 citations
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April 2014 in “PubMed” This rat study found that a PLGA conduit filled with neural crest stem cells derived from hair follicles showed promising results in repairing peripheral nerve injuries, partially restoring sensory function and improving nerve structure.
21 citations
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June 2022 in “Pharmaceutics” This study found that bioactive extracts from goat placenta, particularly when delivered via dissolving microneedles, enhanced fibroblast proliferation and skin regeneration without being toxic to skin cells, suggesting a promising dermal application for improving skin health.
January 2017 in “Journal of Dermatology and Venereology” This study found that Naringenin and Hesperetin significantly increased the proliferation of hair-related cells and suggested potential as natural hair growth-promoting agents.
13 citations
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February 2024 in “Clinical Cosmetic and Investigational Dermatology” This study demonstrated that intradermal treatment with a medical device using Polynucleotides High Purification Technology (PN HPT) significantly improved skin surface, firmness, pigmentation, and radiance in 30 Asian subjects, with benefits lasting up to six months and no adverse events reported.
March 2026 in “Molecules” This review reports that Dang Gui (Radix Angelica sinensis) possesses bidirectional immunoregulatory effects, enhancing immune cell proliferation and function, and may benefit immune-related diseases such as cancer and anemia. It also evaluates regulatory and safety aspects, aiming to guide future research and clinical use.
1 citations
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December 2020 in “Medical lasers” The laser therapy device effectively increased hair growth in people with androgenetic alopecia.
19 citations
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November 2012 in “Cell Communication and Signaling” This study found that Fibroblast growth factor-9 (FGF-9) accelerates epithelial invagination in engineered ectodermal organs and suggests its potential role in organogenesis and regeneration research.
15 citations
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March 2021 in “Journal of Nanobiotechnology” This study developed a nanoscale biomimetic matrix that effectively and stably expands human hair follicle stem cells, offering a new tool for hair follicle reconstruction research.
March 2023 in “Chemical biology & drug design” This study found that 8% Panax notoginseng saponins may promote hair follicle growth in C57BL/6J mice, potentially through the Wnt/β-catenin signaling pathway.
1 citations
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June 2025 in “Fermentation” This study found that solid-state fermentation using probiotic lactic acid bacteria significantly enhanced the antioxidant properties and bioactive composition of Radix Angelica gigas compared to non-fermented herbs, suggesting a potential method for modernizing traditional herbal medicine.
February 2023 in “Medicine in novel technology and devices” This study found that microneedle delivery of Polygonum multiflorum extract led to earlier pigmentation and hair regrowth in mice with androgenetic alopecia.
1 citations
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February 2023 in “Ibrain” This review discusses the neuroprotective properties of Nigella sativa and its nanoformulations for treating neurodegenerative disorders, without presenting new clinical results.
March 2026 in “bioRxiv (Cold Spring Harbor Laboratory)” In this study, researchers developed a new method called Enriched-GF, which enhances growth factor recovery from platelet concentrates through a combination of glass bead activation, freeze-thaw cycling, and calcium stimulation, outperforming conventional methods by providing higher and more consistent yields for regenerative medicine applications.
This study found that local application of nano-liposome-bound EGF at 333.3μg/ml postponed hair growth in rats, unlike lower concentrations or free form.
March 2023 in “Applied and Computational Engineering” This study proposes a deep learning model using CNN with VGG16, VGG19, and MobileNetV2 architectures, achieving high accuracy in classifying scalp diseases from images, potentially facilitating diagnosis and treatment via mobile devices.
26 citations
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September 2018 in “Journal of Molecular Cell Biology” This study observed that Endoglin is crucial for maintaining correct hair follicle cycling and stimulating hair follicle stem cell niches through feedback interactions involving Wnt/β-catenin and Bmp/Smad signaling pathways in a mouse model.
November 2022 in “CARDIOMETRY” This article discusses the potential benefits of GcMAF and oral MAF, developed by "Saisei Mirai", for cancer and other conditions, but reports no new clinical results.
January 2025 in “Journal of Controlled Release” This study developed a gas-propelled microneedle patch with puerarin/quercetin nanoparticles, which demonstrated improved hair-regenerating effects in an androgenetic alopecia mouse model by increasing drug delivery, alleviating oxidative stress, promoting angiogenesis, and rejuvenating senescent cells.
108 citations
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July 2004 in “American Journal of Pathology” This study suggests that nerve growth factor plays a crucial role in the stress-induced termination of hair growth in mice, and its antagonism might offer a therapeutic approach to mitigate stress-related hair loss.
July 2024 in “Journal of Investigative Dermatology” A new test helps find drugs to treat head and neck cancer by targeting c-Rel.
January 2026 in “Biomacromolecules” This study reports that a novel nanolipogel with moderate rigidity (NLG-2.5) enhances transdermal delivery of fucosterol, displaying superior permeability, targeting hair follicles, and promoting hair growth in androgenetic alopecia model mice by inhibiting inflammation and androgen pathways and promoting angiogenesis.
2 citations
,
July 2024 in “Materials Today Communications” In this study, an injectable alginate hydrogel with Fibronectin3 was developed, demonstrating high biocompatibility and ability to enhance wound healing in mice, suggesting promise for clinical application in treating irregular wounds.
1 citations
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January 2004 in “PubMed” In this study, NGF and minoxidil increased the growth of human hair follicles while 17 beta-E2 inhibited it; NGF also neutralized 17 beta-E2's inhibitory effect.
8 citations
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November 1976 in “Journal of Investigative Dermatology” In this study, RNA-sequencing identified differentially expressed genes, including FGF5, FGFR1, and RRAS, that affect the hair follicle growth cycle in Inner Mongolian Cashmere goats.
January 2023 in “Editora Enterprising eBooks” This collection of interdisciplinary studies highlights research from various institutions on topics relevant to Brazilian social development, but it reports no new empirical findings.
1 citations
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January 2016 in “Journal of gastrointestinal & digestive system” The researchers reported that the SAGI PGP procedure resulted in excess weight loss of over 90% in the first year and normalized blood sugar levels without medication among diabetic patients by the first month post-operation.
March 2025 in “Frontiers in Pharmacology” This study developed a hydrogel dressing incorporating angelica polysaccharides, demonstrating enhanced wound healing properties in a mouse model by promoting rapid hemostasis, tissue healing, and new blood vessel formation compared to Tegaderm™ film.