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Androgens, male hormones, affect physical and mental functions, with a decrease leading to health issues like muscle loss, bone disease, and depression, and more research is needed on long-term effects and treatments.

5-alpha reductase inhibitors, like finasteride and dutasteride, are used for prostate issues, hair loss, and excessive hair growth, may help with COVID-19, but can cause sexual and mental health side effects, and their use in preventing prostate cancer needs more examination.

Finasteride may cause lasting sexual and mental health issues, and genetic screening could help prevent them.

The document concludes that ongoing medical therapy is crucial for preventing hair loss, and surgical options can restore hair, with future treatments for hair loss being promising.

A brain-made hormone can protect against memory-related brain damage caused by harmful proteins.

Finasteride affects brain and blood steroids, causing lasting sexual and emotional side effects.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.

Finasteride treatment can decrease certain steroids and increase others, possibly leading to depression symptoms in some cases.

Changing neuroactive steroid levels early in life can affect how adult rats respond to alcohol's stimulating effects.

Changing neuroactive steroids in baby male rats affects their memory and learning differently as they grow up.

Stopping finasteride for male pattern hair loss changes neuroactive steroid levels in the brain and blood.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

GABRA2 gene variations impact alcohol response, and hair loss medication finasteride reduces some effects.

Finasteride, a drug, can block the seizure-preventing effects of a hormone called progesterone in mice.

Men and women have different levels and production of brain steroids, which may affect their risk for certain brain disorders.

5α reductase inhibitors treat hair loss but may cause sexual side effects and risks.

Pregnancy reduces anxiety in rats, but finasteride reverses this effect.

Finasteride use can cause lasting negative effects like sexual dysfunction, depression, anxiety, and cognitive issues.

Fluoxetine's effectiveness as an antidepressant in mice depends on a specific protein activity and a 5-minute pretest.

The steroids allopregnanolone and allotetrahydrodeoxycorticosteron worsened absence seizures in rats.

Seeing trauma causes fear in mice by lowering their natural fear-reducing hormones.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

Progesterone and its metabolites affect myelin protein expression differently in male and female rat Schwann cells.

Cannabinoid and steroid-based drugs could be new treatments for Tourette syndrome, but more research is needed to confirm their effectiveness and safety.

Finasteride reduces alcohol withdrawal effects, especially in female mice.

Former finasteride users showed higher rates of depression and suicidal thoughts compared to those who never used it.

Testosterone improves mood and thinking skills; finasteride has no effect.

Finasteride may increase depression by reducing brain cell growth.

Finasteride reduces alcohol withdrawal severity and anxiety in mice, but may increase withdrawal severity in some cases.

Alcohol in teen years leads to more adult drinking, finasteride doesn't help.