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The study found that certain genes are important for hedgehog skin appendage development and immunity, with spines possibly evolving for protection and infection resistance.

Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.

High CRP levels could indicate vitamin D deficiency in people with alopecia areata.

Alopecia areata is likely an autoimmune disease with unclear triggers, involving various immune cells and molecules, and currently has no cure.

Hair loss involves immune responses, inflammation, and disrupted signaling pathways.

Different immune cells like platelets, mast cells, neutrophils, macrophages, T cells, B cells, and innate lymphoid cells all play roles in skin wound healing, but more research is needed due to inconsistent results and the complex nature of the immune response.

Restoring immune privilege in hair follicles could help treat certain types of hair loss.

Histone modification is key in treating chronic inflammatory skin diseases.

TGFβ's manipulation of inflammation and immune cells affects cancer spread, suggesting new treatment strategies and biomarkers.

T-cells in alopecia areata scalp show abnormal regulation, leading to less inflammation.

Alopecia areata is caused by immune system attacks on hair follicles, often triggered by viral infections.

Recent selection on immune response genes was identified across seven ethnicities.

Alopecia areata is an autoimmune disease causing patchy hair loss, often with other autoimmune disorders, but its exact causes are unknown.

Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.

Researchers found four genes that could help diagnose severe alopecia areata early.

New treatments targeting T-cell pathways are needed for better alopecia areata management.

Hair follicles prevent NK cell attacks to avoid hair loss.

Epidermal keratinocytes start wound healing and inflammation after schistosome infection.

The reviewers found the manuscript on inflammation's role in cancer stem cells to be relevant but suggested it needs clarity, more background information, discussion on immune cells' role in tumors, updated references, and grammar corrections.

The reviewers suggest clarifying the abstract, adding background on inflammation's effect on stem cells and cancer, discussing immune cells' role in tumors, and considering inflammation's potential to reduce cancer growth.

Behçet's Disease may be caused by genetic and environmental factors leading to abnormal immune responses, and stress management and new treatments could improve patient outcomes.

The revised manuscript on how inflammation affects cancer stem cells was accepted after addressing issues with clarity and detail.

Genes related to keratin, skin cell differentiation, and immune functions are key in hedgehog skin and spine development.

CTLA4 gene variants are not linked to alopecia areata in Monterrey's Mexican population.

Reviewers suggest clarifying the abstract, adding background on inflammation's effect on cancer, discussing immune cell roles, including counter studies, and correcting grammar.

Type I interferons play a key role in the development of various skin diseases.

New treatments for skin damage from UV light using stem cells and their secretions show promise for skin repair without major risks.

Both topical calcipotriol and narrowband UVB improved alopecia, but combining them didn't enhance the effect on hair loss severity, despite higher vitamin D3 levels.

The revised study on how inflammation affects cancer stem cells was accepted after improving clarity and structure.

The reviewers suggest major revisions for clarity and inclusion of recent findings on inflammation's role in cancer.