Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

In this review, the researchers identify and discuss promising molecular and genetic targets for lung cancer therapy, suggesting that advancements in understanding these targets could lead to new drug developments and more effective treatments.

This study identifies novel genetic variants in the NOTCH3 and HTRA1 genes associated with CADASIL and CARASIL, highlighting their potential in supporting clinical diagnosis and informing treatment strategies.

This review summarizes various nutritional approaches and supplements, such as the Mediterranean and ketogenic diets and probiotics, as potential strategies to improve polycystic ovary syndrome symptoms, reporting no new clinical results.

This study found that utilizing a clinical pharmacist in perioperative urological services reduced surgical cancellations and resident overtime while improving service efficiency and financial sustainability.

This study found that RSPO1, a Wnt/β-catenin pathway agonist, significantly induces insulin-producing β cell replication and neogenesis in various settings, offering a promising potential therapy for diabetes.

This review discusses Barrett's esophagus, its risk factors, diagnostic methods, and treatment options, emphasizing its potential for malignant degeneration and the importance of personalized treatment based on patient factors.

This review highlights exosomes as a promising treatment for skin damage from UV light, infrared radiation, burns, and disorders due to their anti-inflammatory properties, ability to induce macrophage polarization, and acceleration of skin repair and regeneration.

This review discusses various diagnostic and treatment strategies for canine prostate diseases, including pharmacological options and advanced procedures, but reports no new clinical results.

This study demonstrated that hair follicle cells can be induced to differentiate into cardiomyocyte-like cells in vitro, exhibiting characteristics and spontaneous beating typical of cardiac muscle, without genetic modification.

This review discusses the preventable nature of many cancers due to modifiable risk factors and emphasizes the importance of preventive oncology in reducing the global cancer burden; it reports no new clinical results.

This study found that enhancing quercetin bioavailability with EubioQuercetin significantly improved external aging signs in mice and influenced gut microbiota and intestinal gene expression, suggesting potential modulation through the gut microbiota–intestinal barrier axis.

The study found that enhancing quercetin bioavailability with EubioQuercetin may amplify its anti-aging effects in mice by modulating the gut microbiota and improving intestinal barrier function.

This review highlights new perspectives in genomics and epigenomics for skin rejuvenation, comparing innovative strategies like senolytics and DNA repair modulators with classical treatments, and emphasizing the importance of tailoring therapies using individual genomic profiles for personalized anti-ageing approaches.

In this study, araliadiol, a plant-derived compound, exhibited senomorphic effects in three dermal fibroblast senescence models, suggesting its potential as a topical treatment to mitigate skin aging by reducing certain senescence-related markers and increasing procollagen type I content.

This review discusses the repurposing of auranofin for oncological and non-oncological uses and highlights its early-stage clinical trial findings, suggesting further exploration of its therapeutic potential.

This analysis found that females have a higher lifetime risk of alopecia areata across various regions and time periods, with increased risk associated with higher socio-demographic index levels.

This study provides a comprehensive review of the use of electrospinning technology to create 3D porous structures for bone implants, emphasizing the synergy between biomedicine and materials science necessary for developing orthopedic materials.

In this pilot randomized clinical trial, TRT combined with finasteride increased lean mass, muscle size, and bone mineral density without prostate enlargement in men with spinal cord injury, suggesting potential benefits for body composition and musculoskeletal health.

This research abstract outlines the innovative approach of the Frontiers journal series, which aims to transform academic publishing by providing open access, interdisciplinary journals that employ a rigorous peer-review process to serve both scholarly communities and the public.

This study investigated 130 patients and found a significant inverse correlation between copper content and the copper/zinc ratio in hair samples and the extent of coronary artery disease, while zinc content alone showed no significant relationship with disease extent.

In this study, valproic acid, levetiracetam, and phenytoin were the main anti-seizure medications associated with adverse drug reactions in pediatric epilepsy patients, with younger children and those on polytherapy at higher risk.

This review highlights various plant-based and herbal treatments that reportedly help prevent hair loss and encourage hair growth. It also explores the molecular mechanisms, identified plant compounds, recent technologies such as nanoarchitectonics, and patents related to hair growth promotion.

In this study reviewing recent literature, researchers found limited high-quality evidence supporting the use of adipose-derived stem cells for androgenic alopecia and alopecia areata, suggesting a need for further randomized controlled trials to better assess their efficacy.

This study reported that seed germination and root hair growth were significantly enhanced after exposure to an individual whose depression was treated with Emotional Freedom Techniques, suggesting that human mood may influence seed viability.

This study found that the YH0618 decoction reduced chemotherapy-induced nail discoloration, alopecia, skin hyperpigmentation, and fatigue in cancer patients who completed chemotherapy.

This article highlights advances in various physiological studies, including vitamin E's potential to improve aging-related outcomes in mice, but does not present new experimental results.

This study found that scalp melanoma often occurs in areas with androgenetic alopecia, and patients without alopecia might experience a later diagnosis due to hair coverage, leading to potentially worse outcomes.

This study describes a method to extract and characterize keratin particles from human hair, finding they can encapsulate the anticancer drug Paclitaxel with significant efficiency, releasing it in a pH-dependent manner potentially beneficial for targeted cancer treatment.

This review discusses the potential antidepressant effects of phenylalanine, highlighting its significant activity in laboratory studies, but reports no new clinical findings.

This consensus report outlines Brazilian dermatologists' recommendations for treating alopecia areata, highlighting intralesional corticosteroids for localized cases and systemic therapy for extensive, active disease, along with monitoring side effects.